Area Under the Curve of carotid artery Doppler as a sensitive marker of insulin sensitivity among Iraqi women with polycystic ovarian syndrome: a cross sectional study

Akram, W.; Nori, W.; Zghair, M.A.G.

doi:10.36129/jog.2022.86

Cited by 2 publications

(1 citation statement)

References 33 publications

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“…Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in young age women [11]. It presents with hyperinsulinemia, ovarian dysfunction, and metabolic syndrome.…”

Section: Interpretation and Comparison With Other Literaturementioning

confidence: 99%

Assessment of the long Pentraxin 3 level in polycystic ovarian syndrome-related infertility

Essa¹,

Hameed²

2024

Ital J Gynaecol Obstet

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Objective. To evaluate the role of Pentraxin 3 level in PCOS-related infertility and its correlation with the disease's hormonal profile. Patients and Methods.A case-control study involves a total of 90 women for one year, 30 women diagnosed with PCOS who are fertile, 30 women diagnosed with PCOS who are infertile, and 30 healthy controls, all women in the early follicular phase were sent for baseline investigations: FSH, LH, AMH, Fasting blood sugar, Insulin, Testosterone, TSH, and Pentraxin 3 that were measured by sandwich electrochemiluminescence immunoassay.Results. There were statistically significant variations in LH, LH/FSH ratio, Testosterone levels, and AMH across the groups. The mean of Pentraxin for the fertile PCOS group (4.14 ± 1.97) ng/mL was significantly higher than for the infertile PCOS group (1.39 ± 1.10 ng/Ml) and control (1.99 ± 1.66 ng/mL). For the infertile PCOS group, the correlation of Pentraxin was significantly positive with age and negative with AMH. ROC Curve analysis showed a cutoff value of 1.05 ng/ml with a sensitivity of 46.67% and specificity of 83.33% for the infertile group.Conclusions. Pentraxin 3 level is significantly higher in fertile PCOS patients and lower in the infertile PCOS group in comparison to the control group suggesting its possible role in PCOSrelated infertility.

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“…Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in young age women [11]. It presents with hyperinsulinemia, ovarian dysfunction, and metabolic syndrome.…”

Section: Interpretation and Comparison With Other Literaturementioning

confidence: 99%

Assessment of the long Pentraxin 3 level in polycystic ovarian syndrome-related infertility

Essa¹,

Hameed²

2024

Ital J Gynaecol Obstet

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A Complete Overview of the Polycystic Ovarian Syndrome with Recent Advancement in Clinical Trial

Mukherjee,

Rai,

Ghoshal

et al. 2025

CWHR

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Background: Polycystic ovarian syndrome (PCOS) has emerged as one of the most common endocrine and metabolic disorders seen in women of childbearing age throughout the whole world. The complex pathophysiology, different diagnostic criteria, and various manifestations attached to several environmental factors, including lifestyle influences, have made it one of the most difficult disorders to treat in recent times. In addition, inadequate knowledge among patients and a lack of dedicated approved medications have only enhanced the difficulties in treating such a heterogeneous disorder. Objective: The main objective of this review-type paper is to provide a detailed overview of PCOS along with the current concept of a clinical stance in this complex multigenic disorder. Method: The following databases were used for literature searches: PubMed, Frontiers, Science Direct, Springer, Wiley, and MDPI. For the purpose of finding pertinent articles and contents, the keywords “PCOS; hirsutism; psychological burden; obesity” and others of a similar nature were utilized. Conclusion: PCOS is a complicated hormonal, metabolic, and psychological condition with many different clinical manifestations. It is among the most prevalent causes of infertility. Before considering any medication choices, lifestyle modifications should be considered the primary therapeutic prescription for PCOS-related infertility. According to recent studies, PCOS does not affect the risk of ovarian or breast cancer, but it does raise the risk of endometrial cancer in women of all ages. These results suggest that PCOS may increase the risk of gynaecological cancer morbidity. The following stage is ovulation stimulation, which is best accomplished with letrozole and is followed by clomiphene citrate. Women who had not responded to the first-line oral ovulatory medicine were given gonadotropins as a backup. Early detection of girls with a high propensity to develop PCOS will be made possible by a comprehensive knowledge of the condition's etiology. Adolescent PCOS will be better managed overall, related comorbidities will be prevented, and quality of life will increase with customized therapeutic approaches.

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Area Under the Curve of carotid artery Doppler as a sensitive marker of insulin sensitivity among Iraqi women with polycystic ovarian syndrome: a cross sectional study

Cited by 2 publications

References 33 publications

Assessment of the long Pentraxin 3 level in polycystic ovarian syndrome-related infertility

Assessment of the long Pentraxin 3 level in polycystic ovarian syndrome-related infertility

A Complete Overview of the Polycystic Ovarian Syndrome with Recent Advancement in Clinical Trial

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