ARFI elastography for the evaluation of diffuse thyroid gland pathology: Preliminary results

Sporea, Ioan; Şirli, Roxana; Bota, Simona; Vlad, Mihaela; Popescu, Alina; Zosin, Ioana

doi:10.4329/wjr.v4.i4.174

Cited by 77 publications

(105 citation statements)

References 24 publications

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“…Moreover, a statistically significant difference in ARFI values was acquired between left and right thyroid lobe [43]. Subsequent study by those researchers confirmed their preliminary findings [44]. Ruchala et al using SSW revealed that CAT increases the thyroid tissue stiffness, which remains unchanged despite the introduction of L-thyroxin (LT4) treatment [22].…”

Section: Chronic Autoimmune Thyroiditissupporting

confidence: 69%

Zastosowanie sonoelastografii w diagnostyce i monitorowaniu leczenia zapaleń oraz choroby autoimmunologicznej tarczycy

Ruchała

Szmyt

Sławek

et al. 2015

Endokrynologia Polska

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Sonoelastography (USE) is a constantly evolving imaging technique used for the noninvasive and objective estimation of tissue stiffness. Several USE methods have been developed, including Quasi-Static or Strain Elastography and Shear Wave Elastography. The utility of USE has been demonstrated in differentiating between malignant and benign thyroid lesions. Recently, USE has been applied in the evaluation of thyroiditis and autoimmune thyroid disease (AITD). Thyroid inflammatory illnesses constitute a diverse group of diseases and may manifest various symptoms. These conditions may share some parallel clinical, biochemical, and ultrasonographic features, which can lead to diagnostic difficulties. USE may be an additional tool, supporting other methods in the diagnosis and treatment monitoring of thyroid diseases, other than thyroid nodular disease. The aim of this article was to analyse and summarise the available literature on the applicability of different elastographic techniques in the diagnosis, differentiation and monitoring of various types of thyroiditis and AITD. Advantages and limitations of this technique are also discussed. StreszczenieSonoelastografia (USE) jest stale rozwijającą się techniką obrazowania stosowaną do nieinwazyjnej i obiektywnej oceny sprężystości tkanki. Jak dotąd opracowano wiele metod USE, które można podzielić na dwie zasadnicze grupy: quasi-statyczną elastografię i elastografię fali poprzecznej (SWE). Wykazano wysoką skuteczność USE w różnicowaniu łagodnych i złośliwych zmian ogniskowych w gruczole tarczowym. Coraz częściej USE znajduje zastosowanie w ocenie zapaleń gruczołu tarczowego, w tym autoimmunologicznej choroby tarczycy (AITD). Zapalne choroby tarczycy stanowią bardzo zróżnicowaną grupę chorób, których wczesne objawy są nieswoiste. Trudności diagnostyczne mogą wynikać zarówno ze wspólnych cech klinicznych, biochemicznych, jak i ultrasonograficznych zapaleń tarczycy. Sonoelastografia może być uznana za dodatkowe narzędzie, wspierające inne stosowane metody w diagnostyce i monitorowaniu leczenia chorób tarczycy innych niż choroba guzkowa tarczycy. Celem niniejszego artykułu była analiza i podsumowanie dostępnej literatury na temat możliwości zastosowania technik elastograficznych w rozpoznawaniu, różnicowaniu i monitorowaniu różnych typów zapalenia gruczołu tarczowego. Przedstawiono zarówno wady, jak i zalety stosowania tej techniki w chorobach tarczycy. (Endokrynol Pol 2014; 65 (6): 520-531)

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Section: Chronic Autoimmune Thyroiditissupporting

confidence: 69%

Zastosowanie sonoelastografii w diagnostyce i monitorowaniu leczenia zapaleń oraz choroby autoimmunologicznej tarczycy

Ruchała

Szmyt

Sławek

et al. 2015

Endokrynologia Polska

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“…We did not find any study containing information about the appearance of MTCs in soelastography, which is believed to be an important improvement on conventional US. This has been described as a valuable tool in differentiating between benign and malignant thyroid nodules [16,17], diagnostic of other thyroid diseases, such as Graves' disease, chronic or subacute thyroiditis [18][19][20].…”

Section: Discussionmentioning

confidence: 99%

Cechy sonograficzne raków rdzeniastych tarczycy — przegląd systematyczny i metaanaliza

Woliński

Rewaj-Łosyk

Ruchała

2014

Endokrynologia Polska

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Introduction: Thyroid nodular goitre is one of the most common endocrine disorders. Differentiating between benign and malignant lesions is an emerging challenge in endocrinological practice. Ultrasonography (US) remains the most commonly applied method in the preliminary assessment of lesions and is the basis for the decision as to fine needle aspiration biopsy (FNAB) and further diagnostics. Many studies have evaluated the diagnostic value of US malignancy features. However, they focused mainly on papillary thyroid cancer (PTC). It remains unclear whether other types of thyroid carcinoma (TC) are also characterised by the same US features. The aim of this study was to assess the usefulness of US features considered as markers in the diagnosis of medullary thyroid cancer (MTC). Material and methods:The PubMed/MEDLINE and Cochrane Library databases were searched to identify studies on US features of MTCs. The random-effects model was used to calculate pooled sensitivity and specificity and odds ratios (OR) -if a comparison with PTCs was available. Results: Hypoechogenicity was present in 83.4% of MTCs, and 32.7% were markedly hypoechogenic. None of the 157 MTCs was hyperechogenic. Sensitivity of halo absence was 88.9%, but irregular margins were present in 38.0%. 35.5% of MTCs had microcalcifications, and 27.0% had macrocalcifications. 14.4% presented 'taller than wide feature' (higher anteroposterior than transverse diameter). Apart from macrocalcifications, all these features occurred insignificantly less often in MTCs than in PTCs. Conclusions: US features commonly considered as markers of malignancy can be useful also in the diagnostics of MTCs. However, MTCs tend to possess suspicious US features slightly less often than PTCs. Some features, such as hyperechogenicity, can be considered to be strong markers of benign status. Although the US appearance of the thyroid lesion is an important diagnostic factor, it is worth remembering that it does not allow for a definitive differentiation between benign and malignant nodules. In the case of MTCs, as well as other TCs, US examination remains a valuable diagnostic tool, but should always be interpreted carefully in the context of other examinations.

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“…Elastography Sporea et al reported a cut-off value >2.53 m/s using shear wave elastography (SWE) for differentiation between normal thyroid and diffuse thyroid diseases, with a positive predictive value >90% [46]. They also found a statistically significant difference in velocity values in autoimmune pathology with a value of 2.07±0.44 m/s in Graves' disease compared with 2.68±0.50 m/s in chronic autoimmune thyroiditis [47].…”

Section: Conventional B-mode Ultrasoundmentioning

confidence: 89%

“…There were no significant differences between the TS values obtained with linear vs convex probes and when 5 vs 10 measurements were taken in each lobe (median values). ARFI SWE seems to be a useful method for the evaluation of diffuse thyroid gland pathology and is able to predict with sufficient accuracy the presence of diffuse thyroid diseases (AUROC=0.80) [46,47].…”

Section: Conventional B-mode Ultrasoundmentioning

confidence: 99%

Thyroid Ultrasound: State of the Art Part 1 – Thyroid Ultrasound reporting and Diffuse Thyroid Diseases

et al. 2017

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Accurate differentiation of focal thyroid nodules (FTL) and thyroid abnormalities is pivotal for proper diagnostic and therapeutic work-up. In these two part articles, the role of ultrasound techniques in the characterization of FTL and evaluation of diffuse thyroid diseases is described to expand on the recently published World Federation in Ultrasound and Medicine (WFUMB) thyroid elastography guidelines and review how this guideline fits into a complete thyroid ultrasound exam.

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ARFI elastography for the evaluation of diffuse thyroid gland pathology: Preliminary results

Abstract: ARFI seems to be a useful method for the assessment of diffuse thyroid gland pathology.

Cited by 77 publications

References 24 publications

Zastosowanie sonoelastografii w diagnostyce i monitorowaniu leczenia zapaleń oraz choroby autoimmunologicznej tarczycy

Zastosowanie sonoelastografii w diagnostyce i monitorowaniu leczenia zapaleń oraz choroby autoimmunologicznej tarczycy

Cechy sonograficzne raków rdzeniastych tarczycy — przegląd systematyczny i metaanaliza

Thyroid Ultrasound: State of the Art Part 1 – Thyroid Ultrasound reporting and Diffuse Thyroid Diseases

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