Argan oil: Which benefits on cardiovascular diseases?

Cherki, M.; Berrougui, Hicham; Drissi, A.; Adlouni, A.; Khalil, Abdelouahed

doi:10.1016/j.phrs.2006.02.004

Cited by 59 publications

(76 citation statements)

References 50 publications

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“…These studies have fully confirmed the traditionally known cholesterol-and triacylglycerol-lowering effects of argan oil in humans, together with its hypotensive effect. Consequently, argan oil consumption clearly reduces cardiovascular risks, and argan oil can be used as an antiatherogenic oil [26]. In addition, argan oil has been shown to possess antioxidant properties [27,28].…”

Section: Scientifically Investigated Pharmacological Properties Of Armentioning

confidence: 99%

Argan oil: Occurrence, composition and impact on human health

Charrouf¹,

Guillaume²

2008

Eur. J. Lipid Sci. Technol.

154

129

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Edible argan oil is traditionally prepared by Berber women who manually crunch the roasted kernels of Argania spinosa fruits. Unroasted kernels furnish a cosmetic-grade oil. Argan groves are currently shrinking due to unfavorable conditions. To stop this trend, a program aimed at increasing the argan tree economical value is in progress in Morocco. Its concept is that the natives will preserve argan trees only if the major part of the wealth resulting from the argan grove production directly benefits them. Because of its high dietary value, argan oil has appeared as the best derivative to rapidly satisfy such assumption. Consequently, year after year, cooperatives have been implanted to produce argan oil of high quality on a large scale. The delicate hazelnut taste of argan oil, combined with its high level in unsaturated fatty acids, has allowed its swift commercial success and, nowadays, argan oil of standardized quality is marketed worldwide. Moroccan farmers are now beginning to plant argan trees, confirming the full success of this ambitious program. This review summarizes the methods used to prepare argan oil, its composition, the strategies available to certify argan oil quality, and finally the impact of argan oil on human health.

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Section: Scientifically Investigated Pharmacological Properties Of Armentioning

confidence: 99%

Argan oil: Occurrence, composition and impact on human health

Charrouf¹,

Guillaume²

2008

Eur. J. Lipid Sci. Technol.

154

129

View full text Add to dashboard Cite

show abstract

“…a-, b-, and d-tocopherols represent 2.4 to 6.5%, 0.1 to 0.3%, and 6.2 to 12.8%, respectively, of the total tocopherol fraction. The simultaneous presence of high levels of unsaturated fatty acids, c-tocopherol, and sterols is currently believed to be the reason for the hypocholesterolemiant, hepato and cardioprotective properties of argan oil [19,20]. These compounds could also provide a cancer chemoprotective effect [21].…”

Section: Argan Oilmentioning

confidence: 99%

Enhancing the value of argan oil is the best mean to sustain the argan grove economy and biodiversity, so far

Charrouf¹,

Harhar²,

Gharby³

et al. 2008

OCL

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“…Considering its rich composition in antioxidant compounds and unsaturated fat, A. spinosa can be used as a nutritional intervention in the CVD diseases prevention [21].…”

Section: Introductionmentioning

confidence: 99%

The Protective Effects of Argania Spinosa Seeds Against Hyperhomocystenemia Induced by High Methionine Diet in Mice

Aklil

Zerizer

Kabouche

2017

Int J Pharm Pharm Sci

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Objective: Hyperhomocysteinemia (HHCY), oxidative stress and decreased antioxidant capacities lead to several clinical manifestations and particularly, cardiovascular and liver diseases. Our aim in this study was to investigate the protective effects of Argania spinosa powdered seeds against high methionine diet-induced HHCY, oxidative stress and damages in the aorta, and heart of mice.Methods: Adult male Mus Musculus was systematically divided into four groups of similar mean body weights and fed for 21 d with control and experimental diets. The control group (F) was fed with white bread (0.50 mg/mice), group (M) was fed with L-methionine (500 mg/kg/day), group (MP) was fed with L-methionine (500 mg/kg/day) plus A. spinosa powdered seeds 150 mg/kg), and the group (P) was treated with A. spinosa powdered seeds (150 mg/kg/day). The experimental diets were given in white bread (0.50 mg/mice). After 3 weeks of treatments, homocysteine (HCY) concentrations, hepatic antioxidant status and histological sections of aorta and heart were determined.Results: Consumption of high methionine diet led to an increase in plasma HCY, reduced the concentrations of GSH, and the enzyme catalase. These were associated with the loss and degeneration of endothelium, fenestration and formation of foam cells of the aorta, also the alteration of the cardiac muscle. However, administration of A. spinosa powdered seeds in combination with methionine decreased the concentration of HCY from (10.04±0.83 μmol/l) to (7.26±0.46 μmol/l), increased catalase activity from (45.82±5.83 m mol/mg protein) to (62.26±3.32 m mol/mg protein), and ameliorated histological changes. Conclusion:A. spinosa powdered seeds were effectives in decreasing plasma HCY level as induced by methionine-enriched diet in mice, and improved the antioxidants defence.

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Argan oil: Which benefits on cardiovascular diseases?

Cited by 59 publications

References 50 publications

Argan oil: Occurrence, composition and impact on human health

Argan oil: Occurrence, composition and impact on human health

Enhancing the value of argan oil is the best mean to sustain the argan grove economy and biodiversity, so far

The Protective Effects of Argania Spinosa Seeds Against Hyperhomocystenemia Induced by High Methionine Diet in Mice

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