Argon laser photocoagulation of port wine stain hemangiomas

Silver, Lester

doi:10.1002/lsm.1900060108

Cited by 27 publications

(4 citation statements)

References 15 publications

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“…Ideally, the evaluation of comparative responses of PWS to different PDL values should involve evaluation of whole lesions. Test areas are generally considered to be good indicators of the benefit of full treatments 29 and are used in practice to assess response to the whole lesion. Grading of treatment response to PDL should ideally involve both clinical grading and objective measurement; however, there are no universally accepted and widely used objective measurements of PWS response to PDL treatment 30–33 .…”

Section: Discussionmentioning

confidence: 99%

A comparative study of a 595-nm with a 585-nm pulsed dye laser in refractory port wine stains

Yung

Sheehan-Dare

2005

British Journal of Dermatology

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Our experience of high fluence PDL in the treatment of refractory PWS suggests patients treated with 585 nm (pulse width 1.5 ms) improve to a similar degree as patients treated with 595-nm PDL (pulse width 1.5 ms). However, the use of the 595-nm PDL with longer pulse widths yields no extra advantage. For those patients who have failed to improve with high-fluence 585-nm PDL (pulse width 1.5 ms), test areas using 595-nm PDL (pulse width 1.5 ms and 6 ms) should be undertaken to ascertain if individual patients may benefit from the longer pulse width 595-nm PDL.

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Section: Discussionmentioning

confidence: 99%

A comparative study of a 595-nm with a 585-nm pulsed dye laser in refractory port wine stains

Yung

Sheehan-Dare

2005

British Journal of Dermatology

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“…The control box displays the following: power delivered at the tissue (0-10 W), pulse length (30-990 ms) and the hexagonal field sizes (3,5,9,11, and 13 mm).…”

Section: Scanning Technique (St)mentioning

confidence: 99%

Comparative study of the “point‐by‐point technique” and the “scanning technique” for laser treatment of port‐wine stain

Mordon¹,

Rotteleur²,

Buys³

et al. 1989

Lasers Surg Med

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Photocoagulation using the argon laser has been proven to be an effective method for the treatment of port-wine stains (PWS). However, it is very difficult to reproduce the parameters of laser treatment. This leads to inaccurate energy dosages secondary to the difference in treatment patterns. The aim of this study was to compare the conventional point-by-point technique (PT) for PWS treatment against a new scanning technique (ST) using a device called "Hexascan" (PREIN & Partners, Ferney-Voltaire, France). A total of 249 patients (171 females and 78 males) using the argon laser have been studied in a retrospective study. Clinical results are presented. For each technique, blanching and hypertrophic scarring were examined. The results are classified into two groups: satisfactory and unsatisfactory. The clinical results show that the ST with the Hexascan is superior to the conventional PT. Scarring is drastically reduced because overdosage and overheating are avoided. Because of precisely controlled spot patterns, quality and homogeneity of blanching is improved. Treatment time can be reduced to 20% of that of the PT.

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“…Argon and other continuous and quasicontinuous visible light lasers were first used to treat PWS. The risk of scarring in the pink and immature group was as high as 25% (Silver, 1986). The pulsed dye laser (PDL) was then developed based on the concept of selective photothermolysis .…”

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confidence: 99%

Mechanisms of Microvascular Response to Laser Pulses

Suthamjariya

Farinelli

Koh

et al. 2004

Journal of Investigative Dermatology

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"Selective photothermolysis" is widely used for treating vascular lesions. In order to understand mechanisms of response, we investigated fast events during pulsed laser treatment of microvessels. A high-speed (2000 fps) CCD camera and microscope were used to image hamster cheek pouch microvessels during and after 532 nm and 1064 nm laser pulse exposures. Pulse duration and fluence were varied systematically (1-50 ms, 0-600 J per cm2). Threshold fluences for fast events were determined. On a millisecond time-scale, a specific series of fast events occur, which are wavelength, fluence, irradiance, and pulse duration dependent. In order of increasing fluence we observed: blood coagulation, vasoconstriction, thread-like appearance of the treated vascular segment, vessel disappearance, intravascular cavitation, bubble formation, vessel wall rupture and hemorrhage, and shrinkage of perivascular tissue. With increasing pulse duration, the threshold fluences for coagulation, vessel disappearance, and cavitation increase, and cavitation becomes less violent, conforming to the vessel lumen. Intravascular cavitation did not always rupture the vessel wall, and is not the mechanism for immediate vessel disappearance, a desired endpoint for treating vascular lesions. The apparent mechanism for immediate vessel disappearance is contraction of intravascular blood and perivascular collagen after thermal denaturation. This study suggests that detecting fast events in humans, in real time, may provide useful feedback signals for "smarter" laser devices.

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Argon laser photocoagulation of port wine stain hemangiomas

Cited by 27 publications

References 15 publications

A comparative study of a 595-nm with a 585-nm pulsed dye laser in refractory port wine stains

A comparative study of a 595-nm with a 585-nm pulsed dye laser in refractory port wine stains

Comparative study of the “point‐by‐point technique” and the “scanning technique” for laser treatment of port‐wine stain

Mechanisms of Microvascular Response to Laser Pulses

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