“…It is undeniable that the socio-scientific issue can practice argumentation skills. There have been several previous studies, and it is recommended to be discussed or debated on social scientific issues to improve students' scientific argumentation skills (Anisa, Widodo, & Riandi, 2017;Herlanti et al, 2012;Sandoval, Enyedy, Redman, & Xiao, 2019;Yacoubian & Khishfe, 2018). Then, the issue of cloning of sacrifice animals, endangered animals, and humans has also led to a pro-contra debate among students using reasons from various aspects such as religion, health, social economy, and science .…”