Arimidex inhibition on proliferation of human breast solid tumors measured by ATP bioluminescence

Tse, Edith Yuk-Ting; Loo, Wings T.Y.; Cheung, Mary; Chow, Louis W.C.; Cheng, Carter W.N.

doi:10.1016/j.lfs.2004.09.016

Cited by 4 publications

(2 citation statements)

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“…2 That finding serves as the basis of the application of ATP-depleting agents in the therapy of cancer which may result in the tumor growth inhibition or regression, respectively. 3 It was found that the ATP assay may be used to determine the metabolic rate before and after administration of the cytotoxic drugs to the breast tumor in vitro, 4 thereby enabling determination of the susceptibility of a patient to a chemotherapeutic drug. This allows reducing the number of unsuccessfully administered drugs which are devastating for the patient's health.…”

Section: ■ Introductionmentioning

confidence: 99%

“…It was found that the ATP assay may be used to determine the metabolic rate before and after administration of the cytotoxic drugs to the breast tumor in vitro, thereby enabling determination of the susceptibility of a patient to a chemotherapeutic drug. This allows reducing the number of unsuccessfully administered drugs which are devastating for the patient’s health.…”

Section: Introductionmentioning

confidence: 99%

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Molecularly Imprinted Hybrid Adsorbents for Adenine and Adenosine-5′-triphosphate

et al. 2012

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Submicrometer-sized silica gel particles were coated with a polyanion and a polycation bearing thymine chromophores. The polymer-coated particles were found to selectively adsorb adenine and adenosine-5'-triphosphate (ATP), as compared to other nucleobases and nucleotides, respectively. The adsorption was enhanced by the irradiation of the particles in the presence of adenine which resulted in the molecular imprinting of adenine. ATP adsorption was strongly pH-dependent.

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Section: ■ Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%