Aripiprazole augmentation induced hypertension in major depressive disorder: A case report

Hsiao, Yi-Ling; Chen, Shaw-Ji; Shen, Tsu-Wang; Chang, Chung‐Hsing; Chen, Shao-Tsu

doi:10.1016/j.pnpbp.2010.11.024

Cited by 5 publications

(3 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In addition, Bat-Pitault and Delorme reported hypertension (190/110 mmHg) in an adolescent patient, which was most likely induced by aripiprazole 12. Although Pitchot and Ansseau and Hsiao et al discussed the influence of a concomitant drug,10,11 case one in the current report received aripiprazole only, and high blood pressure developed after aripiprazole. Therefore, it is not likely that the influence of the concomitant drug induced hypertension.…”

Section: Discussionmentioning

confidence: 51%

“…Pitchot and Ansseau indicated that the addition of 5 mg of aripiprazole to 150 mg of venlafaxine in a patient with major depressive disorder led to hypertension (200/110 mmHg) and that aripiprazole discontinuation led to normalized blood pressure within 48 hours 10. Hsiao et al showed high blood pressure (220/110 mmHg), headache, and dizziness after treatment with 90 mg of duloxetine and 5 mg/day of aripiprazole in a depressed patient 11. Moreover, the administration of nifedipine and ramipril did not have an antihypertensive effect, and blood pressures were normalized with a reduction in aripiprazole from 5 mg/day to 2.5 mg/day.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Worsened hypertension control induced by aripiprazole

Yasui‐Furukori¹,

Fujii²

2013

NDT

View full text Add to dashboard Cite

Aripiprazole is widely used in the treatment of schizophrenia and bipolar disorders. Although antipsychotics generally have hypotensive effects, two cases were identified that demonstrated hypertension during the switch from other antipsychotics to aripiprazole. The hypertensive state of these patients recovered after switching back to other antipsychotics, and these cases suggest that aripiprazole may lead to hypertension.

show abstract

Section: Discussionmentioning

confidence: 51%

Section: Discussionmentioning

confidence: 99%

Worsened hypertension control induced by aripiprazole

Yasui‐Furukori¹,

Fujii²

2013

NDT

View full text Add to dashboard Cite

show abstract

“…Previous anecdotal reports have documented the occurrence of hypertension during therapy with aripiprazole and resolution following its discontinuation. 15 – 18 While none of these reports has conclusively demonstrated the mechanism for this hypertension, Borras and Constant 18 noted successful treatment with propranolol, suggesting that the sympathetic nervous system with adrenergic hyperactivity was the primary mechanism for the alterations in BP.…”

Section: Discussionmentioning

confidence: 99%

Clevidipine resistance in a patient taking aripiprazole and methylphenidate

Jacklen¹,

Campagna²,

Tobias³

2014

JEP

View full text Add to dashboard Cite

Various factors may be responsible for blood pressure alterations during perioperative care. When these physiologic alterations require treatment, several therapeutic options are available. Clevidipine is an ultrashort-acting, intravenous L-type calcium channel antagonist of the dihydropyridine class. Anecdotal experience has demonstrated its efficacy in various clinical scenarios in the pediatric population. We report apparent resistance to the vasodilatory effects of clevidipine in a 13-year-old girl who presented for anesthetic care during posterior spinal fusion for neuromuscular scoliosis whose chronic medication regimen included aripiprazole and methylphenidate for the treatment of depression and attention-deficit/hyperactivity disorder. We discuss the potential interaction of aripiprazole and methylphenidate with the calcium channel antagonists and cellular mechanisms responsible for the resistance to the vasodilatory effects of clevidipine.

show abstract

Schizophrenia and Related Psychoses

2021

The Maudsley Prescribing Guidelines in Psychiatry

View full text Add to dashboard Cite

Despite disagreements about nomenclature, patients who develop schizophrenic or schizophrenialike symptoms in later life are often seen in clinical practice. Questions about the etiology of late-life psychotic disorders and about their similarities or differences from early-onset disorders remain unanswered. Neuroimaging techniques have been used to study patients with late onset of psychosis, and in substantial subgroups of patients (from 25% to 100% in various studies) compared with agematched control subjects, structural and functional abnormalities have been found. We review the literature on imaging in late-life schizophrenia and related psychotic disorders, and we present data from our own investigations of patients with these disorders. We discuss the potential usefulness of imaging evaluations in patients with late-onset disorders, and we offer suggestions for future investigations.

show abstract

Aripiprazole augmentation induced hypertension in major depressive disorder: A case report

Cited by 5 publications

References 8 publications

Worsened hypertension control induced by aripiprazole

Worsened hypertension control induced by aripiprazole

Clevidipine resistance in a patient taking aripiprazole and methylphenidate

Schizophrenia and Related Psychoses

Contact Info

Product

Resources

About