“…Adjunctive OFC was often associated with significant weight gain of .10% or $10% (NNH, 9; 95% CI, [5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20], sedation (NNH, 5; 95% CI, 3-12), abnormal metabolic laboratory results (NNH, 10; 95% CI, 5-29), and elevated prolactin (NNH, 6; 95% CI, 4-11). Adjunctive quetiapine had a very high rate of reported sedation (NNH, 3; 95% CI, 2-3) and was also linked to abnormal metabolic laboratory results (NNH, 6; 95% CI, 4-9) and significant weight gain of $7% (NNH 37; 95% CI, 12-594).…”