Aripiprazole-related alopesia: A case report

Demir, Arzu Çalışkan; Özcan, Özlem

doi:10.5455/jtomc.2017.06.090

Cited by 3 publications

(3 citation statements)

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“…died [20]. In our study, three deaths (5.3%) and four amputations (7%) were detected, and our study did not include only necrotizing infections, making it difficult to compare with the literature.…”

Section: Discussionmentioning

confidence: 79%

Complicated and suppurative skin soft tissue infections: our four-year cases

Kurt¹

2023

Med-Science

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Skin and soft tissue infections (SSTIs) are common community and hospital-acquired infections and rarely result in severe morbidity and mortality. It is not always possible to obtain cultures and isolate the causative agent in these patients, primarily treated with empirical antibiotics. In this retrospective cross-sectional study, 57 patients with complicated SSTI followed between 2018 and 2022 with purulent and necrotizing characteristics or growth in blood cultures were included. Thirty-eight patients (66.7%) were male, and 39 (68.4) had diabetes. In 43 (75.5%) patients, the infection was in the lower extremity and gluteal region. Gram-positive agents were detected in 35 patients (61.4%), Gram-negative agents were found in 13 patients (22.8%), and Gram-positive and Gram-negative mixed growth was detected in 1 patient (1.8%), and no causative agent could be produced in 8 (14%) patients. Of the 21 Staphylococcus aureus produced, 4 (19%) were methicillin-resistant (MRSA). Growth was detected in blood cultures in three patients (5.3%), and all were streptococcal bacteria. It was observed that 31 patients (54.4%) required hospitalization for treatment, and 29 (50.8%) required surgical intervention such as drainage, aspiration, debridement, or amputation. Three patients (5.3%) died, and four (7%) underwent amputation. There was no significant difference between diabetic and non-diabetic patients regarding factors and mortality–morbidity. In the logistic regression analysis, none of the variables of gender, type of causative agent, presence of diabetes, and site of infection significantly affected severe morbidity and mortality. Since it was detected at a low rate in our cases, it can be said that MRSA and P.aeruginosa do not need to be considered in every patient for the initial empirical treatment, Gram-negative rods can be taken into account, especially in diabetics, and broad-spectrum and combined antibiotics are not needed in the vast majority of patients. Microbiological follow-up and sensitivity studies at regional and global scales will need to continue to guide empirical treatments in SSTIs.

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Section: Discussionmentioning

confidence: 79%

Complicated and suppurative skin soft tissue infections: our four-year cases

Kurt¹

2023

Med-Science

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“…Alopecia was also reported to be developed in a pediatric patient, who was diagnosed with mental retardation and irritability at the age of 11 years, three days following aripiprazole 2.5 mg/day therapy. The hair loss decreased one week after discontinuation of aripiprazole and resolved entirely after one month (15). Alopecia was also reported in a female adolescent diagnosed with depression at the age of 16, following four weeks quetiapine therapy at 50 mg/day, and the symptoms were resolved entirely one month after discontinuation of treatment (16).…”

Section: Discussionmentioning

confidence: 84%

Risperidone-induced alopecia in a child with autism spectrum disorder

Ayaydın¹,

Ulgar²

2019

PBS

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Autism spectrum disorder (ASD) is a complex heterogeneous neurodevelopmental disorder. Risperidone appears to be effective in associated behavioral problems with ASD. Alopecia can be drug-induced and has been associated with several psychotropic drugs. Antipsychotics would seem to act by triggering a premature telogen or resting phase, resulting in hair loss. Here, we report a female patient ASD developing alopecia following risperidone use. To the best of our knowledge, this is the first report of alopecia induced by risperidone during treatment of self-injurious behaviours in a child female patient with ASD.

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“…Sadece üstteki deri kaldırılırsa, derin dokuda geride bırakılan lenfatik sisternaların aşırı büyümesi ile nüks görülebilir. 8,17 Bizim her iki olgumuzda da eksizyonel biyopsi uygulanmış olup, izlemde nüks görülmemiştir.…”

Section: Discussionunclassified