Arm lymphedema in patients treated conservatively for breast cancer: Relationship to patient age and axillary node dissection technique

Pezner, Richard D.; Patterson, Mary P.; Hill, L. Robert; Lipsett, James A.; Desai, Kanta R.; Vora, Nayana; Wong, Jeffrey Y.C.; Luk, Kenneth H.

doi:10.1016/0360-3016(86)90005-2

Cited by 155 publications

(69 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Some studies have reported an increased risk among older women [13,43] while others have found no relationship between age and arm lymphedema [22,25]. Why these results vary from study to study is unknown.…”

Section: Discussionmentioning

confidence: 93%

“…Other factors also may influence the risk of arm lymphedema among breast cancer patients, including systemic therapies (chemotherapy and tamoxifen) [22] and patient-related factors such as age [25], body mass index (BMI) [26,27], hypertension [26,28], history of infection [26] and co-morbidities [18,29]. While a few studies have reported an increase in arm lymphedema among racial minorities compared to White women [11,22], study samples have been too small to support any exploration on how lymphedema risk factors may differ among racial groups.…”

mentioning

confidence: 99%

See 1 more Smart Citation

Risk factors for arm lymphedema following breast cancer diagnosis in Black women and White women

Meeske

Sullivan‐Halley

Smith

et al. 2008

Breast Cancer Res Treat

153

137

View full text Add to dashboard Cite

Purpose Lymphedema of the arm is a potential complication of breast cancer therapy. This study examines pre-disposing factors that may operate in conjunction with treatment-related factors in the development of arm lymphedema in a large cohort of White and Black breast cancer survivors. Methods 494 women (271 White and 223 Black) with in situ to Stage III-A primary breast cancer completed a baseline interview within 18 months of diagnosis. Information on lymphedema was collected during a follow-up interview, conducted on average 50 months after diagnosis. Self-reported data were used to classify women with or without lymphedema. Multivariable logistic regression models were developed to identify risk factors for arm lymphedema. Results Arm lymphedema was associated with younger age at diagnosis (odds ratio, OR per year of age = 0.96; 95% confidence interval, CI = 0.93-0.99), positive history of hypertension (OR = 2.31; 95% CI = 1.38-3.88), obesity (OR for body mass index, BMI> or =30 = 2.48; 95% CI = 1.05-5.84) and having had surgery where 10 or more lymph nodes were excised (OR = 2.16; 95% CI = 1.12-4.17). While Black women had higher prevalence of arm lymphedema than White women (28% vs. 21%), race was not associated with lymphedema risk in models adjusted for multiple factors (adjusted OR = 1.01; 95% CI = 0.63-1.63). Conclusion Risk of arm lymphedema did not differ significantly for Black and White women. Risk factors identified in this study offer opportunities for interventions (weight loss, control of blood pressure, use of sentinel node biopsy where possible) for reducing incidence of lymphedema or controlling the symptoms associated with this condition.

show abstract

Section: Discussionmentioning

confidence: 93%

mentioning

confidence: 99%

Risk factors for arm lymphedema following breast cancer diagnosis in Black women and White women

Meeske

Sullivan‐Halley

Smith

et al. 2008

Breast Cancer Res Treat

153

137

View full text Add to dashboard Cite

show abstract

“…The second one consists of disease-related factors such as stage at diagnosis, nodal status, and location of the tumor in the breast. The third class consists of patient and clinicalrelated factors such as age, BMI, infection, and excessive use of extremity [1,[22][23][24]. In the literature, a high BMI is a risk factor for BCRL and the severity (high stage and grade) of lymphedema [11,25,26].…”

Section: Discussionmentioning

confidence: 99%

The role of occupational upper extremity use in breast cancer related upper extremity lymphedema

et al. 2009

View full text Add to dashboard Cite

Group-3 had the worst BCRL clinical stage and grade status and other breast cancer treatment related morbities. Occupations that require greater use of the upper extremities. At present there is a need for closer monitoring of patients with more severe BCRL. Potential exacerbating and maintaining factors of functional limitations and pain need to considered so that clinical management addresses these in relation to daily use of the affected UE.

show abstract

“…Pezner et al [21] described arm edema as mild, moderate or severe depending on the difference between arm circumference at various points from the elbow when the affected arm is compared with the unaffected arm. Stillwell [22] has criteria with a range from insignificant to severe based on the percentage difference in the size of the normal arm when compared with the affected arm.…”

Section: Discussionmentioning

confidence: 99%

The Comparison of Two Different Physiotherapy Methods in Treatment of Lymphedema after Breast Surgery

Karadibak

Ufuk

Saydam

et al. 2005

Breast Cancer Res Treat

View full text Add to dashboard Cite

show abstract

Arm lymphedema in patients treated conservatively for breast cancer: Relationship to patient age and axillary node dissection technique

Cited by 155 publications

References 12 publications

Risk factors for arm lymphedema following breast cancer diagnosis in Black women and White women

Risk factors for arm lymphedema following breast cancer diagnosis in Black women and White women

The role of occupational upper extremity use in breast cancer related upper extremity lymphedema

The Comparison of Two Different Physiotherapy Methods in Treatment of Lymphedema after Breast Surgery

Contact Info

Product

Resources

About