Aromatase inhibitors for subfertile women with polycystic ovary syndrome

Abstract

Analysis 4.1. Comparison 4 Aromatase inhibitors compared to laparoscopic ovarian drilling, Outcome 1 Live birth rate. Analysis 4.2. Comparison 4 Aromatase inhibitors compared to laparoscopic ovarian drilling, Outcome 2 Ovarian hyperstimulation syndrome rate.

Combined metformin‐clomiphene in clomiphene‐resistant polycystic ovary syndrome: a systematic review and meta‐analysis of randomized controlled trials

“…Therefore, it does not have the adverse anti‐estrogenic effects of clomiphene on cervical mucus and endometrium . Consequently, it has been tried in women with CCR‐PCOS at doses of 2.5–7.5 mg/day on days 3–7 of the menstrual cycle . A potential safety concern regarding the newborns was initially raised ; however, recent data have supported its safety .…”

Evaluation of periodontal status in different phenotypes of polycystic ovary syndrome in untreated patients of early reproductive age: A case–control study

“…Polycystic ovary syndrome (PCOS) is one of the most frequent endocrine diseases in women, which is associated with multiple reproductive abnormalities and metabolic disorders. [1][2][3] Based on the Rotterdam criteria 4 which are, presence of clinical or biochemical hyperandrogenism (HA), chronic ovulatory dysfunction (OD) and polycystic ovarian morphology (PCOM), phenotypes of PCOS are classified as follows; phenotype A: HA + OD + PCOM; phenotype B: HA + OD; phenotype C: HA + PCOM and phenotype D: OD + PCOM. 5 Periodontal diseases are defined as a set of infectious and inflammatory conditions affecting the periodontium, which is called periodontitis or gingivitis.…”

Focal Adhesion Proteins, Vinculin and Integrin β5, During Early Pregnancy in Rat Uterine Epithelial Cells: Anastrozole Favors their Normal Distribution

“…A daily dose of 1mg/kg anastrozole (Sigma-Aldrich Co., St. Louis, MO, USA) for 5 days is the standard recommended dose to achieve ovulation in humans (Franik et al, 2014). A 12-14 week mature female Wistar rat weighs between 200-250 g and has a 4-day estrous cycle, so a single dose of anastrozole administered at pro-estrus was deemed appropriate.…”