Aromatic and cannabinoid profiles of Cannabis inflorescences and seed oils: A comprehensive approach for variety characterization

Moreno-Chamba, Bryan; Salazar-Bermeo, Julio; Hosseinian, Farah; Martin-Bermudo, Francisco; Aguado, Manuel; De la Torre, Rosa; Martínez-Madrid, María Concepción; Valero, Manuel; Martí, Nuria; Saura, Domingo

doi:10.1016/j.indcrop.2024.118143

Industrial Crops and Products

2024

DOI: 10.1016/j.indcrop.2024.118143

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Aromatic and cannabinoid profiles of Cannabis inflorescences and seed oils: A comprehensive approach for variety characterization

Bryan Moreno-Chamba,

Julio Salazar-Bermeo,

Farah Hosseinian

et al.

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2024

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Cited by 3 publications

References 26 publications

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Secondary metabolite profiles and anti‐SARS‐CoV‐2 activity of ethanolic extracts from nine genotypes of Cannabis sativa L.

Schadich,

Kaczorová,

Béres

et al. 2024

Archiv der Pharmazie

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This study deals with the comprehensive phytochemical composition and antiviral activity against SARS‐CoV‐2 of acidic (non‐decarboxylated) and neutral (decarboxylated) ethanolic extracts from seven high‐cannabidiol (CBD) and two high‐Δ9‐tetrahydrocannabinol (Δ9‐THC) Cannabis sativa L. genotypes. Their secondary metabolite profiles, phytocannabinoid, terpenoid, and phenolic, were determined by LC‐UV, GC‐MS, and LC‐MS/MS analyses, respectively. All three secondary metabolite profiles, cannabinoid, terpenoid, and phenolic, varied significantly among cannabinoid extracts of different genotypes. The dose–response analyses of their antiviral activity against SARS‐CoV‐2 showed that only the single predominant phytocannabinoids (CBD or THC) of the neutral extracts exhibited antiviral activity (all IC50 < 10.0 μM). The correlation matrix between phytoconstituent levels and antiviral activity revealed that the phenolic acids, salicylic acid and its glucoside, chlorogenic acid, and ferulic acid, and two flavonoids, abietin, and luteolin, in different cannabinoid extracts from high‐CBD genotypes are implicated in the genotype‐distinct antagonistic effects on the predominant phytocannabinoid. On the other hand, these analyses also suggested that the other phytocannabinoids and the flavonoid orientin can enrich the extract's pharmacological profiles. Thus, further preclinical studies on cannabinoid extract formulations with adjusted non‐phytocannabinoid compositions are warranted to develop supplementary antiviral treatments.

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Secondary metabolite profiles and anti‐SARS‐CoV‐2 activity of ethanolic extracts from nine genotypes of Cannabis sativa L.

Schadich,

Kaczorová,

Béres

et al. 2024

Archiv der Pharmazie

View full text Add to dashboard Cite

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A method of maize seed variety identification based on near-infrared spectroscopy combined with improved DenseNet model

Zhou,

Guan,

et al. 2024

Microchemical Journal

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How Do Consumers Describe Cannabis? Using a Sorting Task to Create a Lexicon to Describe Cannabis

Gorman,

McSweeney

2024

Journal of Sensory Studies

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Cannabis consumers' preference while selecting cannabis products, specifically dried flower, has been undergoing a drastic change as more consumers have begun considering the impact that flavor has on their purchasing intent of different cannabis species (including Indica, Sativa, and or hybrid varieties). As such, the objective of this study was to quantify consumers' sensory perceptions of cannabis strains currently on the market. The researchers used Natural Language Processing (NLP) and online North American cannabis retailers, cannabis user reviews, and other informative cannabis websites to identify 107 different descriptors. Cannabis consumers (n = 123) were asked to complete a free word sorting task on the 107 most frequently cited sensory descriptors identified using NLP, as well as identify which attributes they associated with high and low‐quality cannabis. The consumers sorted the descriptors into 10 different categories (fruit, berry/dried fruit, savory, floral, spices, spicy, potent, smoke, roasted, and confectionary). As the cannabis market continues to grow and mature in North America, this study presents a baseline of how consumers describe different cannabis varieties.

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Aromatic and cannabinoid profiles of Cannabis inflorescences and seed oils: A comprehensive approach for variety characterization

Cited by 3 publications

References 26 publications

Secondary metabolite profiles and anti‐SARS‐CoV‐2 activity of ethanolic extracts from nine genotypes of Cannabis sativa L.

Secondary metabolite profiles and anti‐SARS‐CoV‐2 activity of ethanolic extracts from nine genotypes of Cannabis sativa L.

A method of maize seed variety identification based on near-infrared spectroscopy combined with improved DenseNet model

How Do Consumers Describe Cannabis? Using a Sorting Task to Create a Lexicon to Describe Cannabis

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