Arrhenoblastoma of Ovary: Case Report and Histological Review

Sertoli-leydig cell tumors: A clinicopathologic study of 34 cases

“…17 The tumor is said to be approximately one-fifth as common as the corresponding sex-cord-stromal tumor recapitulating the cells of the ovary, the granulosatheca cell tumor, and accounts for less than 0.5% of all ovarian tumors.' 6 We are aware of only two large series of cases of S-L tumor that were personally studied by the authors, and the mortality rates differed widely, being 3 and 34%, respectively. ",13 Three series collected from the literature had recurrence or metastasis in 12 to 22% of Several other tabulations of cases without calculated mortality figures have been reported."'…”

Arrhenoblastoma

“…During this period there have been nearly 100,000 deliveries and 79,500 gynaecological operations. Javert and Finn (1951), Hughesdon and Fraser ( 1953 ), Pedowitz and O'Brien (1960), Foster (1962), O'Hern and Neubecker (1962) and Novak and Long (1963) have reviewed the literature and added cases of their own. It appears, from the above reviews, that only about 250 authentic cases have been reported since Pick (1905), first described a non-virilising tumour and Bell (1915) one with similar histological features and virilisation.…”

“…The histogenesis has been reviewed by Hughesdon and Fraser (1953) and Novak and Long (1963) and the tumours are now generally accepted as arising from primitive ovarian mesenchyme. Schneider ( 1960) and Sandberg (1962) believe that any histological type of tumour may be associated with any observed endocrine effect adducing further support for this thesis.…”