Arrhythmia burden and related outcomes in Eisenmenger syndrome

Baskar, Shankar; Horne, Philippa; Fitzsimmons, Samantha; Khoury, Philip R.; Vettukattill, Joseph; Niwa, Koichiro; Agaki, Teiji; Spence, Mark S.; Sakazaki, Hisanori; Veldtman, Gruschen

doi:10.1111/chd.12481

Congenital Heart Disease

2017

DOI: 10.1111/chd.12481

|View full text |Cite

Arrhythmia burden and related outcomes in Eisenmenger syndrome

Shankar Baskar

Philippa Horne

Samantha Fitzsimmons

et al.

Abstract: Arrhythmias are common among patients with Eisenmenger syndrome occurring in around 1 in 5 individuals and are associated with all-cause mortality and sudden death.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2018

2024

Publication Types

Select...

Article5

Relationship

Self Cite0

Independent5

Authors

Journals

Cited by 8 publications

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Eisenmenger Syndrome in Adults: Treatment Pattern and Prognostic Factors in the Advanced Pulmonary Vasodilator Era

Kim

Song

et al. 2018

Pediatr Cardiol

View full text Add to dashboard Cite

Patients with Eisenmenger syndrome (ES) have a higher mortality rate than patients with simple congenital heart disease (CHD). To determine factors associated with death in the era of advanced pulmonary vasodilator treatment, we analyzed the characteristics of adult ES patients depending on underlying CHD. Simple septal defects and patent ductus arteriosus were classified as simple CHD, and other conditions were classified as complex CHD. Sixty-seven adult ES patients (50.7% women) were reviewed retrospectively. CHD was diagnosed at a median of 10.0 years of age and ES was diagnosed at 18.6 years. Thirteen patients (19.4%) died; the median age was 38.6 years (IQR 32.2-47.8). In a multivariate analysis, patients with SpO < 85% had a higher mortality rate than others [hazard ratio (HR) 9.7; 95% confidence interval (CI) 1.002-95.2, p = 0.05]. In simple CHD patients, those with a low platelet count (< 100 × 10/L) or low SpO (< 85%) were at a higher risk of death than those without (HR 16.32, 95% CI 1.25-2266.31, p = 0.032; and HR 38.91, 95% CI 3.44-5219.41, p = 0.001, respectively). Advanced pulmonary vasodilators were used more in survivors than in non-survivors (48.1% vs. 15.4%, p = 0.032). Low SpO and platelet count were related to mortality in adult ES, especially in those with simple CHD. Therefore, careful attention should be paid to the care of adult ES patients with this tendency; active pulmonary vasodilator treatment should be considered.

show abstract

Eisenmenger Syndrome in Adults: Treatment Pattern and Prognostic Factors in the Advanced Pulmonary Vasodilator Era

Kim

Song

et al. 2018

Pediatr Cardiol

View full text Add to dashboard Cite

show abstract

Pulmonary Hypertension in Adult Congenital Heart Disease–Related Heart Failure

Kusner,

Krasuski

2024

Heart Failure Clinics

View full text Add to dashboard Cite

Incidence and clinical characteristics of sudden cardiac death in adult congenital heart disease

Moore

Kotchetkova

et al. 2018

International Journal of Cardiology

View full text Add to dashboard Cite

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Arrhythmia burden and related outcomes in Eisenmenger syndrome

Abstract: Arrhythmias are common among patients with Eisenmenger syndrome occurring in around 1 in 5 individuals and are associated with all-cause mortality and sudden death.

Cited by 8 publications

References 16 publications

Eisenmenger Syndrome in Adults: Treatment Pattern and Prognostic Factors in the Advanced Pulmonary Vasodilator Era

Eisenmenger Syndrome in Adults: Treatment Pattern and Prognostic Factors in the Advanced Pulmonary Vasodilator Era

Pulmonary Hypertension in Adult Congenital Heart Disease–Related Heart Failure

Incidence and clinical characteristics of sudden cardiac death in adult congenital heart disease

Contact Info

Product

Resources

About