Arrhythmias and Late Sudden Death After Myocardial Infarction

Denborough, M. A.; Lovell, R. R. H.; Nestel, P. J.; Goble, Alan J.

doi:10.1016/s0140-6736(68)91354-8

Cited by 47 publications

(7 citation statements)

References 10 publications

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“…Four (two with permanent right bundle-branch block) of our 18 survivors to six weeks have since died, three of them within a year of infarction, and though four patients have not yet been followed for 12 months the one-year mortality is already 12%. Denborough et al (1968), in a series of 412 patients with acute myocardial infarction who survived to leave hospital, reported a similar mortality at one year.…”

Section: Discussionmentioning

confidence: 79%

Bundle-branch Block in Acute Myocardial Infarction

Hunt¹,

Sloman²

1969

BMJ

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Summary: Bundle-branch block was present in 41 out of 415 patients admitted to a coronary care unit with acute myocardial infarction and was associated with more severe clinical infarction and an overall mortality of 56%. It is probable that permanent bundle-branch block develops soon after infarction and that most of the patients with permanent block have had clinically severe infarction. Bundle-branch block developing during observation is usually transient, and the later it develops the sooner it resolves.Analysis of the arrhythmias and clinical course of the patients suggests that those with bundle-branch block and shock and those in whom bundle-branch block is present on admission may benefit from the use of a demand pacemaker attached to a transvenous pacemaker catheter, though the dividends of pacing may be small and the risks of the procedure significant Post-mortem examination of 17 hearts showed extensive infarction, usually involving the septum, and severe coronary artery disease.

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Section: Discussionmentioning

confidence: 79%

Bundle-branch Block in Acute Myocardial Infarction

Hunt¹,

Sloman²

1969

BMJ

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“…The association of early and late arrhythmias was also noted by Spracklen et al (1968), who recorded that in their group of 11 patients with late ventricular dysrhythmias, seven had had significant arrhythmias in the unit. A study of patients who left hospital alive after myocardial infarction recorded that arrhythmias in hospital were more closely related to late sudden death than to death after chest pain (Denborough et al, 1968). The frequent observation of ventricular fibrillation by the cardiac arrest team suggests that a ventricular arrhythmia may have precipitated cardiac arrest or sudden death in many of these patients.…”

Section: Discussionmentioning

confidence: 99%

Sudden Death in Hospital after Discharge from Coronary Care Unit

Thompson¹,

Sloman²

1971

BMJ

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“…Electrical instability of the heart as a definite cause of late ventricular dysrhythmias can only be incriminated with certainty in patients in whom an irritable myocardium persists after the acute phase. Denborough et al (1968) postulated an increased sensitivity to catecholamines as a cause of late ventricular dysrhythmias. Bjerkelund (1957) suggested that a sudden disturbance of electrical conduction of the heart might lead to ventricular fibrillation or asystole.…”

Section: Discussionmentioning

confidence: 99%

“…There is no evidence that anticoagulant drugs at present in use can reduce the incidence of further coronary occlusion or of late sudden death after myocardial infarction (Bjerkelund, 1957;Aspenstrbm. and Korsan-Bengsten, 1964;Denborough et al, 1968 (Smirk and Palmer, 1960). Increasing sinus bradycardia, complete heart block, and a previous cardiac arrest are warnings of possible asystole, usually unsalvable (Meltzer and Kitchell, 1966;Lawrie et al, 1967).…”

Section: Discussionmentioning

confidence: 99%

Late Ventricular Dysrhythmias after Myocardial Infarction

Spracklen¹,

Besterman²,

Everest³

et al. 1968

BMJ

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Summary: Serious ventricular dysrhythmias occurred in hospital after discharge from a coronary intensive care unit in 11 out of 142 patients with myocardial infarction. Previous rhythm changes, hypotension, and left ventricular failure were common findings; only one of these patients had an uneventful previous course. Four patients were resuscitated and left hospital; six were resuscitated but died at varying periods up to eight days after the event; one patient could not be resuscitated. Recent coronary occlusion or further myocardial infarction was demonstrated in 7 of these 11 patients and presumably accounted for the dysrhythmia.

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Arrhythmias and Late Sudden Death After Myocardial Infarction

Cited by 47 publications

References 10 publications

Bundle-branch Block in Acute Myocardial Infarction

Bundle-branch Block in Acute Myocardial Infarction

Sudden Death in Hospital after Discharge from Coronary Care Unit

Late Ventricular Dysrhythmias after Myocardial Infarction

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