Arsenic biomethylation by photosynthetic organisms

Ye, Jun; Rensing, Christopher; Rosen, Barry P.; Zhu, Yan

doi:10.1016/j.tplants.2011.12.003

Cited by 218 publications

(153 citation statements)

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“…In addition, many microbes, both prokaryotic and eukaryotic, have arsM genes for inorganic arsenite [As(III)] S-adenosylmethionine methyltransferases that methylate inorganic As(III) to mono-, di-, and tri-methylated species (4,5). The genes encoding arsenic transforming enzymes are widely distributed, and these arsenic biotransformations have been proposed to play significant roles in the arsenic biogeocycle and in remodeling the terrain in volcanic areas such as Yellowstone National Park and regions of the world with high amounts of arsenic in soil and water such as West Bengal and Bangladesh (3,6).…”

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confidence: 99%

A C⋅As lyase for degradation of environmental organoarsenical herbicides and animal husbandry growth promoters

Yoshinaga

Rosen

2014

Proc. Natl. Acad. Sci. U.S.A.

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127

170

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Arsenic is the most widespread environmental toxin. Substantial amounts of pentavalent organoarsenicals have been used as herbicides, such as monosodium methylarsonic acid (MSMA), and as growth enhancers for animal husbandry, such as roxarsone (4-hydroxy-3-nitrophenylarsonic acid) [Rox(V)]. These undergo environmental degradation to more toxic inorganic arsenite [As(III)]. We previously demonstrated a two-step pathway of degradation of MSMA to As(III) by microbial communities involving sequential reduction to methylarsonous acid [MAs(III)] by one bacterial species and demethylation from MAs(III) to As(III) by another. In this study, the gene responsible for MAs(III) demethylation was identified from an environmental MAs(III)-demethylating isolate, Bacillus sp. MD1. This gene, termed arsenic inducible gene (arsI), is in an arsenic resistance (ars) operon and encodes a nonheme iron-dependent dioxygenase with C·As lyase activity. Heterologous expression of ArsI conferred MAs(III)-demethylating activity and MAs(III) resistance to an arsenic-hypersensitive strain of Escherichia coli, demonstrating that MAs(III) demethylation is a detoxification process. Purified ArsI catalyzes Fe 2+ -dependent MAs(III) demethylation. In addition, ArsI cleaves the C·As bond in trivalent roxarsone and other aromatic arsenicals. ArsI homologs are widely distributed in prokaryotes, and we propose that ArsI-catalyzed organoarsenical degradation has a significant impact on the arsenic biogeocycle. To our knowledge, this is the first report of a molecular mechanism for organoarsenic degradation by a C·As lyase.herbicide resistance | growth promoter degradation

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mentioning

confidence: 99%

A C⋅As lyase for degradation of environmental organoarsenical herbicides and animal husbandry growth promoters

Yoshinaga

Rosen

2014

Proc. Natl. Acad. Sci. U.S.A.

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127

170

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“…It has been reported that bacteria, anaerobic archaea and halophiles in soils or sludges can methylate As [60][61][62][63]. Arsenic biomethylation has been observed in numerous cyanobacteria and algae as well [14,57]. Furthermore, methylcobalamin-dependent nonenzymatic methylation of As has been reported for numerous anaerobic prokaryotes [64].…”

Section: Arsenic Speciation Modulated By Micro-organismsmentioning

confidence: 99%

“…Organic As such as monomethylarsonic acid (MMA), dimethylarsinic acid (DMA) and trimethylarsine (TMA) which may have been derived from microbial and algal biomethylation could also be present in paddy soils as a minor component [14,16].…”

Section: Arsenic Species In Paddy Soilmentioning

confidence: 99%

“…Although higher plant is believed to be unable to methylate As by itself and no gene encoding ArsM has as yet been identified in the genome of any higher plants, genes capable of As methylation widely exist in many microorganisms [14]. Recently, Meng et al [105] expressed an arsM gene from the soil bacterium Rhodopseudomonas palustris in Japonica rice and then monomethylarsenate (MAs(V)) and dimethylarsenate (DMAs(V)) were detected successfully in the roots and shoots of the transgenic rice, and the transgenic rice could give off 10-fold greater volatile arsenicals than the wild type.…”

Section: The Manipulation Of Arsenic Methylation and Volatilizationmentioning

confidence: 99%

“…In addition to abiotic factors (pH, Eh of soils, adsorption of metallic oxides and organic matter (OM), etc. ), it has been suggested that microorganisms play a major role in modulating As speciation (reduction, oxidation and methylation) and its mobility [13,14].…”

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Effects of microbial processes on the fate of arsenic in paddy soil

2012

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Arsenic (As) is a metalloid toxic to organisms including humans. Arsenic in rice represents a significant exposure pathway for the general population, particularly for those subsisting on rice. Arsenic transformation, namely reduction, oxidation and methylation, in soil-rice systems has fundamental impacts on its mobility and toxicity. In addition to soil chemical properties (pH, Eh, metallic oxides, organic matter), microorganisms play critical roles in As transformation and mobility in paddy soil, such as through ArsM (As(III) S-adenosylmethyltransferase) and interactions with iron oxides or organic matters. Arsenic species in paddy soil directly influence As speciation in rice grain because the methylated As species in rice are mainly derived from microbial methylation in paddy soil. This paper aims to provide an overview on the status of the knowledge and gaps on the chemical aspects of As transformation in soil-rice system in conjunction with microbial ecology and functional genes. In addition, potential pathways (manipulation of microorganisms in paddy soil and genetic engineering) to decrease total As and/or inorganic As in rice grain are proposed.

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Application ofShewanellato Water Treatment Issues

Szeinbaum¹,

Toporek²,

Shin³

et al. 2019

Encyclopedia of Water

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Shewanella drives a variety of environmentally important processes, including the biogeochemical cycling of carbon, metals, metalloids, and radionuclides. The ability of Shewanella to deliver electrons extracellularly also renders this genus valuable for applications of contaminant remediation and energy generation in water treatment processes. Although the first Shewanella species was isolated and studied as a model metal‐reducing microorganism over thirty years ago, only recently has research focused on employing Shewanella to drive water treatment processes. This article examines current and prospective applications of Shewanella to water treatment issues, highlighting biochemical details associated with each technology. The technologies include the remediation of metal‐contaminated environments, the generation of electricity from wastewater streams, the removal of hazardous contaminants under anaerobic conditions, and precious metal recovery in combination with formation of novel biocatalysts.

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Arsenic biomethylation by photosynthetic organisms

Cited by 218 publications

References 69 publications

A C⋅As lyase for degradation of environmental organoarsenical herbicides and animal husbandry growth promoters

A C⋅As lyase for degradation of environmental organoarsenical herbicides and animal husbandry growth promoters

Effects of microbial processes on the fate of arsenic in paddy soil

Application ofShewanellato Water Treatment Issues

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