Arsenic biomethylation by the microorganismapiotrichum humicola in the presence of l-methionine-methyl-d3

Cullen, William R.; Li, Hao; Pergantis, Spiros A.; Eigendorf, Guenter K.; Mosi, Andrew A.

doi:10.1002/aoc.590090703

Cited by 32 publications

(23 citation statements)

References 23 publications

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“…The advantages of hydride generation atomic absorption spectrometry (AAS) in analysis come from its much lower detection limits-parts per billion compared to parts per million for normal AAS-and from a lowered requirement upon matching the sample matrix which befalls normal AAS (59). At a pH of Ͻ4, arsenite is reduced to arsine itself, AsH 3 ; other conversions of oxyacids can be represented as follows: (CH 3 ) n AsO(OH) 3Ϫn 3 (CH 3 ) n AsH 3Ϫn where n ϭ 1 to 3 (68,69). Hence, methylarsonate and dimethylarsinate yield, respectively, monomethylarsine and dimethylarsine.…”

Section: Biomethylation and Bioalkylationmentioning

confidence: 99%

“…Nonvolatile di-and trimethylarsenic species were identified in cultures of C. humiculus, and a dimethylarsenic compound was identified in cultures of the marine alga Polyphysa penicilus (68,69) by the hydride generation technique (see above). When [C 2 H 3 ]methionine was used as a methyl donor, the 2 Hlabeled nonvolatile metabolites produced 2 H-labeled arsines.…”

Section: Gsh ¡ Gs-sg ϩ 2hmentioning

confidence: 99%

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Microbial Methylation of Metalloids: Arsenic, Antimony, and Bismuth

Bentley

Chasteen

2002

Microbiol Mol Biol Rev

518

316

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A significant 19th century public health problem was that the inhabitants of many houses containing wallpaper decorated with green arsenical pigments experienced illness and death. The problem was caused by certain fungi that grew in the presence of inorganic arsenic to form a toxic, garlic-odored gas. The garlic odor was actually put to use in a very delicate microbiological test for arsenic. In 1933, the gas was shown to be trimethylarsine. It was not until 1971 that arsenic methylation by bacteria was demonstrated. Further research in biomethylation has been facilitated by the development of delicate techniques for the determination of arsenic species. As described in this review, many microorganisms (bacteria, fungi, and yeasts) and animals are now known to biomethylate arsenic, forming both volatile (e.g., methylarsines) and nonvolatile (e.g., methylarsonic acid and dimethylarsinic acid) compounds. The enzymatic mechanisms for this biomethylation are discussed. The microbial conversion of sodium arsenate to trimethylarsine proceeds by alternate reduction and methylation steps, with S-adenosylmethionine as the usual methyl donor. Thiols have important roles in the reductions. In anaerobic bacteria, methylcobalamin may be the donor. The other metalloid elements of the periodic table group 15, antimony and bismuth, also undergo biomethylation to some extent. Trimethylstibine formation by microorganisms is now well established, but this process apparently does not occur in animals. Formation of trimethylbismuth by microorganisms has been reported in a few cases. Microbial methylation plays important roles in the biogeochemical cycling of these metalloid elements and possibly in their detoxification. The wheel has come full circle, and public health considerations are again important

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Section: Biomethylation and Bioalkylationmentioning

confidence: 99%

Section: Gsh ¡ Gs-sg ϩ 2hmentioning

confidence: 99%

Microbial Methylation of Metalloids: Arsenic, Antimony, and Bismuth

Bentley

Chasteen

2002

Microbiol Mol Biol Rev

518

316

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“…4a and is consistent with that reported earlier. [31][32][33][34][35] Arsine is the only product arising from the irradiation of As(III) in a solution of formic acid.…”

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confidence: 99%

“…Trimethylarsine has been reported earlier as arising from bacterial cultures. [31][32][33][34][35][36] Dimethylethylarsine has been detected in landfill and sewage gas, 37 natural gas 38 as well as river and harbor sediments. 39 Triethylarsine has been detected under conditions similar to those which give rise to dimethylethylarsine.…”

mentioning

confidence: 99%

Photochemical alkylation of inorganic arsenic : Part 1. Identification of volatile arsenic species

Guo

Sturgeon

Mester

et al. 2005

J. Anal. At. Spectrom.

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Access and use of this website and the material on it are subject to the Terms and Conditions set forth at Photochemical alkylation of inorganic arsenic. Part 1. Identification of volatile arsenic species Guo, X. M.; Sturgeon, R.; Mester, Z.; Gardner, G. J.http://nparc.cisti-icist.nrc-cnrc.gc.ca/npsi/jsp/nparc_cp.jsp?lang=fr L'accès à ce site Web et l'utilisation de son contenu sont assujettis aux conditions présentées dans le site LISEZ CES CONDITIONS ATTENTIVEMENT AVANT D'UTILISER CE SITE WEB. NRC Publications Record / Notice d'Archives des publications de CNRC:http://nparc.cisti-icist.nrc-cnrc.gc.ca/npsi/ctrl?action=rtdoc&an=8898768&lang=en http://nparc.cisti-icist.nrc-cnrc.gc.ca/npsi/ctrl?action=rtdoc&an=8898768&lang=fr READ THESE TERMS AND CONDITIONS CAREFULLY BEFORE USING THIS WEBSITE.http://nparc.cisti-icist.nrc-cnrc.gc.ca/npsi/jsp/nparc_cp.jsp?lang=en Vous avez des questions? Nous pouvons vous aider. Pour communiquer directement avec un auteur, consultez la première page de la revue dans laquelle son article a été publié afin de trouver ses coordonnées. Si vous n'arrivez pas à les repérer, communiquez avec nous à PublicationsArchive-ArchivesPublications@nrc-cnrc.gc.ca. Questions? Contact the NRC Publications Archive team atPublicationsArchive-ArchivesPublications@nrc-cnrc.gc.ca. If you wish to email the authors directly, please see the first page of the publication for their contact information. NRC Publications Archive Archives des publications du CNRCThis publication could be one of several versions: author's original, accepted manuscript or the publisher's version. / La version de cette publication peut être l'une des suivantes : la version prépublication de l'auteur, la version acceptée du manuscrit ou la version de l'éditeur. For the publisher's version, please access the DOI link below./ Pour consulter la version de l'éditeur, utilisez le lien DOI ci-dessous.http://doi.org/10.1039/b503661eJournal of Analytical Atomic Spectrometry, 20, 8, pp. 702-708, 2005 Photochemical alkylation of inorganic arsenic Volatile arsenic species generated by UV irradiation of aqueous solutions of arsenite in low molecular weight (LMW) carboxylic acid media (formic, acetic, propionic and butyric) were identified using ICP-TOF-MS and GC-MS. Cryogenic trapping-GC-MS reveals that inorganic arsenite can be alkylated to yield AsH 3 in the presence of formic acid, trimethylarsine in acetic acid, triethylarsine in propionic acid and tripropylarsine in butyric acid solutions. Mixed ligand arsenic species such as methylarsine, dimethylarsine, dimethylethylarsine and diethylmethylarsine are also formed when a mixture of acids is used. Using 0.05 mg l À1 As(III) as the test solution in 3.1 M acetic acid, a methylation efficiency of approximately 75% was achieved.

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“…Following the pioneering work of Gosio (23) and Challenger et al (6,7), the mechanism for the biomethylation of arsenic has been studied extensively with various fungi (10,15), bacteria (3), archaea (3,30), and mammals (1,38,41), including humans (13). As proposed by Challenger, the biomethylation of selenium and tellurium follows the same mechanism as arsenic but, in general, studies investigating these processes are rather rare (16,22,38).…”

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confidence: 99%

Production of Volatile Derivatives of Metal(loid)s by Microflora Involved in Anaerobic Digestion of Sewage Sludge

Michalke¹,

Wickenheiser

Mehring³

et al. 2000

Appl Environ Microbiol

193

136

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Gases released from anaerobic wastewater treatment facilities contain considerable amounts of volatile methyl and hydride derivatives of metals and metalloids, such as arsine (AsH 3 ), monomethylarsine, dimethylarsine, trimethylarsine, trimethylbismuth (TMBi), elemental mercury (Hg 0 ), trimethylstibine, dimethyltellurium, and tetramethyltin. Most of these compounds could be shown to be produced by pure cultures of microorganisms which are representatives of the anaerobic sewage sludge microflora, i.e., methanogenic archaea (Methanobacterium formicicum, Methanosarcina barkeri, Methanobacterium thermoautotrophicum), sulfate-reducing bacteria (Desulfovibrio vulgaris, D. gigas), and a peptolytic bacterium (Clostridium collagenovorans). Additionally, dimethylselenium and dimethyldiselenium could be detected in the headspace of most of the pure cultures. This is the first report of the production of TMBi, stibine, monomethylstibine, and dimethylstibine by a pure culture of M. formicicum.Volatile methyl and hydride derivatives of metal(loid)s are found in gases released from natural environments such as sediments, wetlands (40), and hydrothermal springs (26), as well as from anthropogenic environments such as wastewater treatment plants and waste deposits (18). Some of the compounds are of anthropogenic origin, for example, alkylated tin and lead derivatives, whereas others are produced in environmental settings either due to chemical transalkylation or due to biologically mediated methylation and hydride formation (the addition of a formal hydride ion mediated by an organism) (11,36). The production of volatile metal(loid) compounds is a significant part of the biogeochemical cycles of metals (e.g., Bi, Hg, and Sn) and metalloids (e.g., As, Sb, Se, and Te) because of the increased mobility of the resultant compounds. Additionally, most of the volatile derivatives exhibit higher toxicity than their inorganic counterparts, since organic derivatives are lipophilic and are thus more biologically active (35,36). Exceptions are arsenic and selenium, in which cases the inorganic, nonmethylated forms are more toxic than the methylated derivatives (14).Following the pioneering work of Gosio (23) and Challenger et al. (6, 7), the mechanism for the biomethylation of arsenic has been studied extensively with various fungi (10, 15), bacteria (3), archaea (3, 30), and mammals (1, 38, 41), including humans (13). As proposed by Challenger, the biomethylation of selenium and tellurium follows the same mechanism as arsenic but, in general, studies investigating these processes are rather rare (16,22,38). Mercury biomethylation, on the other hand, has been studied in more detail because of poisonings by methylmercury compounds (4,8,29,33). Although stibine has been implicated as a cause in sudden infant death syndrome (31), up to now, only trimethylantimony was detected as a biovolatilization product of antimony in the headspace of soil samples (24) and of pure cultures of Scopulariopsis brevicaulis (12,27). The biomethylation of inorg...

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Arsenic biomethylation by the microorganismapiotrichum humicola in the presence of l-methionine-methyl-d3

Cited by 32 publications

References 23 publications

Microbial Methylation of Metalloids: Arsenic, Antimony, and Bismuth

Microbial Methylation of Metalloids: Arsenic, Antimony, and Bismuth

Photochemical alkylation of inorganic arsenic : Part 1. Identification of volatile arsenic species

Production of Volatile Derivatives of Metal(loid)s by Microflora Involved in Anaerobic Digestion of Sewage Sludge

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