Arsenic, cadmium, and lead

Patwa, Jayant; Sharma, Abha; Flora, Swaran J.S.

doi:10.1016/b978-0-323-89773-0.00029-1

Cited by 5 publications

(1 citation statement)

References 111 publications

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“…These heavy metals cause damage to various organs after leaving the systemic circulation. However, the great problem associated with these elements is their accumulation over time in various organs and the damage generated by mechanisms such as the breakdown of enzymes, hormones, proteins, and cell membranes, among others, as they have no biological function [ 12 , 13 , 14 , 15 , 16 , 17 , 18 ]. There are also reports of long-term human exposure to low levels of barium (Ba), which is associated with symptoms of diarrhea, cardiac arrhythmia, muscle weakness, anxiety, and nervous system disorders [ 19 , 20 ]; thus, it requires evaluation since its presence is widespread in the environment [ 20 ].…”

Section: Introductionmentioning

confidence: 99%

Inorganic Contaminants in Plant-Based Yogurts Commercialized in Brazil

Rebellato¹,

Fioravanti

Milani³

et al. 2023

IJERPH

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This study aimed to evaluate the content of 11 inorganic elements (Al, Cr, Co, Ni, As, Mo, Cd, Sb, Ba, Hg, and Pb) in commercial plant-based and animal-based yogurts for comparison purposes. The samples were mineralized using a simple and fast ultrasound-assisted acid digestion method at 80 °C for 35 min, and the determination of inorganic elements was performed by ICP-MS. The method was validated according to the INMETRO guide, obtaining recoveries from 80 to 110%, precision from 6 to 15%, and a limit of quantification (LOQ) ranging from 200 µg/kg (Al) to 4 µg/kg (other elements). The element concentrations in the plant-based yogurts were Al(<LOQ-9019.05); Cr(<LOQ-88.14); Co(<LOQ-40.56); Ni(31.71-700.46); As(<LOQ-10.61); Mo(<LOQ-355.70); Cd(<LOQ-4.37); Sb and Hg(<LOQ); Ba(<LOQ-1505.71), and Pb(<LOQ-21.58) µg/kg. The elements Mo and Ba were quantified only in the animal-based yogurts, with levels of 72.54 and 160.76 µg/kg, respectively. The results showed a large variation in the concentration of inorganic elements, which demonstrates the importance of knowing the composition of plant-based foods to ensure the safety and health of consumers.

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Section: Introductionmentioning

confidence: 99%

Inorganic Contaminants in Plant-Based Yogurts Commercialized in Brazil

Rebellato¹,

Fioravanti

Milani³

et al. 2023

IJERPH

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Protective Role of Vitamin B6 Against Teratogenic Effects Induced by Lead in Chick Embryo

Ahmad,

Kanwal,

Inayat

et al. 2024

Birth Defects Research

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BackgroundHeavy metals like lead (Pb) have been used by humans for a very long time, but throughout the industrial revolution, their use expanded, increasing exposure to the metal. Lead, however, has no biological purpose in the human body and is hazardous when it gets into soft tissues and organs. Lead is still used in a variety of industries, including battery manufacturing and car maintenance, despite efforts to limit its usage.ObjectiveThis study investigates the teratogenic and morphometric effects of lead on chick embryos and the potential ameliorative effects of vitamin B6.MethodsTwo hundred fertilized eggs from the golden black chicken were divided into four groups: control, lead acetate, vitamin B6, and lead + vitamin B6.ResultsOn the 14th day, embryos were analyzed. Significant reductions in body weight and size were observed in the lead‐exposed group (33.93 ± 1.27 g) compared to the control (41.12 ± 0.97 g). Pronounced deformities included rudimentary beaks, protruding eyes, tridactyl limbs, hydrocephaly, and neck deformities. Appendicular deformities like phocomelia, amelia, and abnormal phalanges growth were also noted. Vitamin B6 demonstrated therapeutic benefits, significantly improving mean embryo weight in the Lead + Vitamin B6 group (42.37 ± 0.99 g). The lead‐exposed group showed a reduction in maxilla length (3.61 ± 1.30 mm) compared to the Lead + Vitamin B6 group (7.57 ± 0.79 mm). This group also showed reduced severity of muscular dystrophy and bone thinning, with signs of recovery in beak and bone sizes.ConclusionsThe study highlights vitamin B6's beneficial impact in mitigating lead's toxic effects on chick embryonic development.

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Toxicity Potential of Nutraceuticals

Gupta,

Doss

2024

Methods in Molecular Biology

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Arsenic, cadmium, and lead

Cited by 5 publications

References 111 publications

Inorganic Contaminants in Plant-Based Yogurts Commercialized in Brazil

Inorganic Contaminants in Plant-Based Yogurts Commercialized in Brazil

Protective Role of Vitamin B6 Against Teratogenic Effects Induced by Lead in Chick Embryo

Toxicity Potential of Nutraceuticals

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