Arsenic contamination in Bangladesh groundwater: A major environmental and social disaster

Alam, Muhd Nazrul Hisham Zainal; Allinson, Graeme; Stagnitti, Frank; Tanaka, Atsushi; Westbrooke, Martin

doi:10.1080/0960312021000000998

Cited by 185 publications

(96 citation statements)

References 39 publications

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“…However, the concentration of iAs in drinking water needed to produce this effect is an order of magnitude higher than iAs concentrations shown to produce arseniasis symptoms, including diabetes, in humans. For example, in arseniasis-endemic areas of Bangladesh, the concentration of iAs in drinking water can reach 3.4 ppm (Alam et al, 2002). Liver samples from local residents who developed hepatomegaly as a result of drinking water with 0.22 to 2 ppm iAs contained from 500 to 6,000 μg As/kg dry weight (Mazumder, 2005).…”

Section: Discussionmentioning

confidence: 99%

Examination of the effects of arsenic on glucose homeostasis in cell culture and animal studies: Development of a mouse model for arsenic-induced diabetes

Paul

Hernández-Zavala

Walton

et al. 2007

Toxicology and Applied Pharmacology

125

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Previous epidemiologic studies found increased prevalences of type 2 diabetes mellitus in populations exposed to high levels of inorganic arsenic (iAs) in drinking water. Although results of epidemiologic studies in low-exposure areas or occupational settings have been inconclusive, laboratory research has shown that exposures to iAs can produce effects that are consistent with type 2 diabetes. The current paper reviews the results of laboratory studies that examined the effects of iAs on glucose metabolism and describes new experiments in which the diabetogenic effects of iAs exposure were reproduced in a mouse model. Here, weanling male C57BL/6 mice drank deionized water with or without the addition of arsenite (25 or 50 ppm As) for 8 weeks. Intraperitoneal glucose tolerance tests revealed impaired glucose tolerance in mice exposed to 50 ppm As, but not to 25 ppm As. Exposure to 25 and 50 ppm As in drinking-water resulted in proportional increases in the concentration of iAs and its metabolites in the liver and in organs targeted by type 2 diabetes, including pancreas, skeletal muscle and adipose tissue. Dimethylarsenic was the predominant form of As in the tissues of mice in both 25 and 50 ppm groups. Notably, the average concentration of total speciated arsenic in livers from mice in the 50 ppm group was comparable to the highest concentration of total arsenic reported in the livers of Bangladeshi residents who had consumed water with an order of magnitude lower level of iAs. These data suggest that mice are less susceptible than humans to the diabetogenic effects of chronic exposure to iAs due to a more efficient clearance of iAs or its metabolites from target tissues.

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Section: Discussionmentioning

confidence: 99%

Examination of the effects of arsenic on glucose homeostasis in cell culture and animal studies: Development of a mouse model for arsenic-induced diabetes

Paul

Hernández-Zavala

Walton

et al. 2007

Toxicology and Applied Pharmacology

125

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“…[2] In several parts of the world, including Bangladesh, inorganic arsenic of geological origin is found in groundwater used for drinking, leading to chronic arsenic poisoning in humans. [1] Anthropogenic sources of arsenic are of great environmental concern. High levels of arsenic are found in copper, lead, gold and uranium mine tailings and the use of pesticides, herbicides and silvicides has increased the levels of arsenic in the environment.…”

Section: Introductionmentioning

confidence: 99%

“…Excessive arsenic exposure has been associated with increased incidence of skin, lung and possibly liver cancer in humans. [1] Arsenic can be released to the environment through natural weathering, volcanic action, volatilisation, mining and other industrial activities. [2] In several parts of the world, including Bangladesh, inorganic arsenic of geological origin is found in groundwater used for drinking, leading to chronic arsenic poisoning in humans.…”

Section: Introductionmentioning

confidence: 99%

Arsenic accumulation, biotransformation and localisation in bertha armyworm moths

Andrahennadi

Pickering

2008

Environ. Chem.

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Environmental context. Insects play an important role in the impact of environmental pollutants such as arsenic. They may accumulate arsenic to high levels, potentially modifying its chemical form, which affects the insects' toxicity to predators such as fish and birds. Here we use synchrotron X-ray techniques to determine the distribution and chemical form of arsenic in larva, pupa and adult of the bertha armyworm moth.Abstract. Insects are important in bioaccumulation and dispersal of environmental contaminants such as arsenic, and biotransformation of arsenic to various chemical forms directly impacts its toxicity to insects and to their predators. In a model study, the toxic effects and biotransformation of arsenic were examined in larvae, pupae and adults of bertha armyworm moth (Mamestra configurata Walker) (Lepidoptera: Noctuidae). A synthetic diet containing 100 µM arsenate caused reduced larval survival and increased pupal stage duration but no effect on pupal weight or larval stage duration. Synchrotron X-ray absorption spectroscopy (XAS) showed that larvae biotransformed dietary arsenate to yield predominantly trivalent arsenic coordinated with three aliphatic sulfurs, modelled as As III -tris-glutathione. Similar species were found in pupae and adults. XAS imaging with micro X-ray fluorescence imaging revealed highly localised arsenic species, and zinc and copper within the gut. The implication of these arsenic species in the diets of predators is discussed.

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“…Developing countries per capita waste generation rate is less due to lower purchasing capacity but aggregated volume is high (Cairncross and Feachem, 1993). Unfair and partial solid waste management (SWM) accelerates environmental pollution and put public health at risks (Alam et al, 2002). In addition, uncontrolled population growth enhances daily generated wastes volume and thus creates environmental snags and economic loss (Salequzzaman et al, 2001).…”

Section: Introductionmentioning

confidence: 99%

Status of Household Solid Waste and People’s Perception on its Management at Sitakunda Upazila, Chittagong

et al. 2017

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Urban household solid waste (HSW) is well-known, but has little knowledge about the rural areas and sub-cities. The quest of the study was to investigate current HSW management system and people's attitude towards it's at Sitakunda Upazila. The study was conducted through a semi-structured questionnaire survey by interviewing 150 households from 3 different socioeconomic groups. The results showed that on an average each household generated 1.26 kg/day wastes which stands at 0.24 kg/person/day in the study area. However, HSW generation is positively correlated with family size (r xy =0.991, p˂0.05), average age of family members (r xy =0.455, p˂0.01), and monthly earnings (r xy =0.999, p˂0.01) of the households. Amidst the various categories of wastes, vegetable and food wastes (VFWs) were identified as the highest value 68.4%. In contrast, 24.6% of the generated wastes were recyclable and 75.4% non-recyclable; 82.1% organic and 17.9% inorganic. A large percentage of sampled households opined that present HSW management involves merely partial collection that is also irregular in urban areas but absent in rural areas. Unfair HSW collection was noticed by 58.7% and partial source segregation is also rare 14%. Besides, 42.7% people were found to dispose their daily generated wastes by open dumping and 25.3% nearby lagoon. A large number of people were dissatisfied 68% and only 6.7% were satisfied with the existing HSW management system. In addition, most of the people encountered bad odor problems by 28.7% and wastes spread on roadside by 38%. Significant quantity of recyclable wastes was noticed to collect from households by hawkers/scraps in the study area and very few household were found to use VFWs with cow-dung to generate biogas.

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Arsenic contamination in Bangladesh groundwater: A major environmental and social disaster

Cited by 185 publications

References 39 publications

Examination of the effects of arsenic on glucose homeostasis in cell culture and animal studies: Development of a mouse model for arsenic-induced diabetes

Examination of the effects of arsenic on glucose homeostasis in cell culture and animal studies: Development of a mouse model for arsenic-induced diabetes

Arsenic accumulation, biotransformation and localisation in bertha armyworm moths

Status of Household Solid Waste and People’s Perception on its Management at Sitakunda Upazila, Chittagong

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