Arsenic speciation in water by high-performance liquid chromatography/inductively coupled plasma mass spectrometry-method validation and uncertainty estimation

Abstract

This study reports, for the first time, building the uncertainty budgets for five arsenic species and estimation of the expanded uncertainty (for k = 2). The qualitative and quantitative parameters determined in the validation process indicate that the presented analytical procedure can be applied for the determination of AsB, As(III), DMA, MMA and As(V) in water.

Determination of total arsenic and arsenic species in drinking water, surface water, wastewater, and snow from Wielkopolska, Kujawy-Pomerania, and Lower Silesia provinces, Poland

“…Total arsenic concentration was determined according to ISO 17294–2 ( 2003 ) standard; however, concentration of arsenic species was determined according to methodology developed and fully validated in our laboratory (Komorowicz and Baralkiewicz 2014 ).…”

“…Chemicals and reagents used for total arsenic solutions and arsenic species (inorganic: arsenite (As(III)), and arsenate (As(V)); organic: arsenobetaine (AsB), monomethylarsenic acid (MMA), and dimethylarsenic acid (DMA)) solutions preparation, salts used for mobile phase preparation, buffer solution, reagents used for pH adjustment, as well as other chemicals used throughout the experiment, were described in details in the previously published work (Komorowicz and Baralkiewicz 2014 ). Particular steps of both analytical procedures—for total arsenic determination and for arsenic species determination—are presented on the Fig.…”

“…Arsenic species concentration was determined by commercially available HPLC/ICP-MS technique according to developed and fully validated in our laboratory methodology described previously (ISO/IEC 2005 ; Komorowicz and Baralkiewicz 2014 ). “In-house” traceability defined as trueness was assured by analysis of spiked samples.…”

“…The choice of an adequate analytical method is dictated by the purpose of our analysis, the level of analyte’s concentration in concrete matrix, and the type of compound in which analyte is present. The most often applied strategy is connection of HPLC separation with ICP-MS detection (Komorowicz and Baralkiewicz 2014 ; Bednar et al 2004 ; Shraim et al 2002 ; Deng et al 2009 ; Jabłońska-Czapla et al 2014 ) or AFS detection (Yu et al 2014 ; Gong et al 2006 ; Keller et al 2014 ; Farias et al 2015 ). Coupling of HG system to AAS (Berg et al 2001 ; Affum et al 2015 ); ICP-MS (Musil et al 2014 ), ASF (Aiuppa et al 2003 ; Deng et al 2009 ; Musil et al 2014 ), or ICP-AES (Smedley et al 2002 ) is also quite popular.…”

Study on multielemental speciation analysis of Cr(VI), As(III) and As(V) in water by advanced hyphenated technique HPLC/ICP-DRC-MS. Fast and reliable procedures

“…The enforced values in legal regulations throughout the world are temporary and relate to the total arsenic and chromium. Consequently, there is a need to develop a reliable procedures for the determination of As and Cr species in drinking water, in order to create relevant legal norms [33]. The objective of this work was to develop new analytical procedures for multielemental speciation analysis of highly toxic arsenic and chromium species in drinking water samples using HPLC/ICP-DRC-MS. Special attention was given to the optimization of the HPLC separation and ICP-DRC-MS detection of As(III), As (V) and Cr(VI), to application of DRC in order to eliminate interferences for arsenic and chromium, simultaneously and examination of effects occurring during analyses at low concentration level -about 1 mg L À 1 .…”