The article examines modern culture and art as an area of interdisciplinary knowledge and practices, in the context of both evolutionary and philosophical-anthropological understanding, and pedagogy of higher education. Based on a review of the literature and available evidence of university practices in various regions of the world, the vectors of development, possibilities and potential of interdisciplinarity in professional training of higher education graduates in the field of culture and art are outlined, in particular, with the consideration of STEMAC (Science, Technology, Engineering, Mathematics for Arts & Culture) educational paradigm.