Arteannuin B, a sesquiterpene lactone from Artemisia annua, attenuates inflammatory response by inhibiting the ubiquitin-conjugating enzyme UBE2D3-mediated NF-κB activation

Chen, Hongqing; Hu, Qiongying; Wen, Tian; Luo, Liuling; Liu, Lu; Wang, Lun; Shen, Xiaofei

doi:10.1016/j.phymed.2023.155263

Phytomedicine

2024

DOI: 10.1016/j.phymed.2023.155263

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Arteannuin B, a sesquiterpene lactone from Artemisia annua, attenuates inflammatory response by inhibiting the ubiquitin-conjugating enzyme UBE2D3-mediated NF-κB activation

Hongqing Chen,

Qiongying Hu,

Tian Wen

et al.

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Cited by 4 publications

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The battle between host antiviral innate immunity and immune evasion by cytomegalovirus

Li,

Xie,

et al. 2024

Cell. Mol. Life Sci.

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Cytomegalovirus (CMV) has successfully established a long-lasting latent infection in humans due to its ability to counteract the host antiviral innate immune response. During coevolution with the host, the virus has evolved various evasion techniques to evade the host’s innate immune surveillance. At present, there is still no vaccine available for the prevention and treatment of CMV infection, and the interaction between CMV infection and host antiviral innate immunity is still not well understood. However, ongoing studies will offer new insights into how to treat and prevent CMV infection and its related diseases. Here, we update recent studies on how CMV evades antiviral innate immunity, with a focus on how CMV proteins target and disrupt critical adaptors of antiviral innate immune signaling pathways. This review also discusses some classic intrinsic cellular defences that are crucial to the fight against viral invasion. A comprehensive review of the evasion mechanisms of antiviral innate immunity by CMV will help investigators identify new therapeutic targets and develop vaccines against CMV infection.

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The battle between host antiviral innate immunity and immune evasion by cytomegalovirus

Li,

Xie,

et al. 2024

Cell. Mol. Life Sci.

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UBE2D3 regulated by WTAP-mediated m6A modification inhibits temozolomide chemosensitivity in glioblastoma

Bao,

Sun,

Pan

et al. 2024

Naunyn-Schmiedeberg's Arch Pharmacol

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Demethylzeylasteral alleviates inflammation and colitis via dual suppression of NF-κB and STAT3/5 by targeting IKKα/β and JAK2

Wen,

Liu,

Chen

et al. 2024

International Immunopharmacology

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Arteannuin B, a sesquiterpene lactone from Artemisia annua, attenuates inflammatory response by inhibiting the ubiquitin-conjugating enzyme UBE2D3-mediated NF-κB activation

Cited by 4 publications

References 55 publications

The battle between host antiviral innate immunity and immune evasion by cytomegalovirus

The battle between host antiviral innate immunity and immune evasion by cytomegalovirus

UBE2D3 regulated by WTAP-mediated m6A modification inhibits temozolomide chemosensitivity in glioblastoma

Demethylzeylasteral alleviates inflammation and colitis via dual suppression of NF-κB and STAT3/5 by targeting IKKα/β and JAK2

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