Arteria umbilical única y malformaciones asociadas: Experiencia en el Hospital Clínico de la Universidad de Chile

Austin-Ward, Enrique Daniel; H, Julio Nazer; T, Silvia Castillo; M, Carolina Llanos

doi:10.4067/s0370-41061998000500002

Cited by 3 publications

(12 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Reported rates of associated malformations also varied between 14% [29] and 65% [19], depending on the population under study as well as on the BD classification used.…”

Section: Discussionmentioning

confidence: 99%

“…A few authors [24] have concluded that the perinatal outcomes of newborns with isolated SUA do not differ from those of infants with trivascular cords and that an adverse perinatal outcome is likely the result of the frequent coexistence of other malformations. However, the majority [1,10,14,19,32] hold that even in the absence of other malformations, mortality, low birth weight, and prematurity occur more often in newborns with SUA than in infants with trivascular cords and that the prenatal diagnosis of SUA should lead to an exhaustive monitoring of the fetus [33]. Nevertheless, it is generally agreed that the long-term prognosis is similar in infants with and without SUA.…”

Section: Perinatal Outcomesmentioning

confidence: 99%

“…It has also been associated with maternal diabetes, preeclampsia, and poli-and oligohydramnios [1,12], and its prevalence is about 4 times higher in autopsy reports [13] or when other BDs [12,[14][15][16] (unspecific [10,17,18] or giving rise to recognizable patterns, such as in Potter or caudal regression [19,20]) are present.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Single Umbilical Artery and Associated Malformations in over 5500 Autopsies: Relevance for Perinatal Management

Rittler

Mazzitelli

Fuksman³

et al. 2010

Pediatr Dev Pathol

View full text Add to dashboard Cite

With a birth prevalence rate of about 1%, single umbilical artery (SUA) is the most frequent of all congenital anomalies. It is recognizably associated with a variety of birth defects, but disagreement exists as to whether a SUA can predict an adverse perinatal outcome; disagreement also exists related to if, when present, other birth defects should be ruled out. The aims of the study were to estimate the association between SUA and other birth defects in a series of perinatal autopsies, to establish if preferential associations between SUA and certain birth defects exist, and to quantify the risks for other birth defects when a SUA is diagnosed. In a series of 5539 perinatal autopsies conducted at the Hospital Materno Infantil Ramón Sardá and the Private Laboratory of Perinatal Pathology, Buenos Aires, Argentina, the rate of each malformation (grouped by organ/system) associated with SUA and the risks of associated malformations were estimated. In this series of autopsies, the rate of SUA showed a 10-fold increase when other malformations were present. The risk for other malformations increased significantly, by a 3-fold to 9-fold measure, when a SUA was present. Urinary and gut anomalies showed a preferential association with SUA. The absence of other birth defects lowered the risk of chromosome anomalies associated with SUA in 56% (odds ratio = 0.44). These results, obtained from a series of perinatal autopsies, are in agreement with most observations found in the literature, namely, high association rates between SUA and urinary and cardiovascular anomalies as well as a low risk for chromosome anomalies in SUA cases without other malformations.

show abstract

“…Reported rates of associated malformations also varied between 14% [29] and 65% [19], depending on the population under study as well as on the BD classification used.…”

Section: Discussionmentioning

confidence: 99%

Section: Perinatal Outcomesmentioning

confidence: 99%

See 1 more Smart Citation

Single Umbilical Artery and Associated Malformations in over 5500 Autopsies: Relevance for Perinatal Management

Rittler

Mazzitelli

Fuksman³

et al. 2010

Pediatr Dev Pathol

View full text Add to dashboard Cite

show abstract

“…Gran importancia también tiene el hecho de el alto porcentaje de prematuros en nuestra muestra (55,4%), aún cuando otros autores no encuentran diferencias en la prematuridad entre los niños con AUU y los normales (15). Nuestros hallazgos, sin embargo, están plenamente de acuerdo con lo reportado por otros autores (7). Estos cuatro importantes hechos: asociación con anomalías estructurales mayores, anormalidades cromosómicas y aneuploidías, RCIU y prematuridad, deben obligar a realizar ecografías seriadas y extremar las medidas de control del embarazo cuando se hace el diagnóstico prenatal de AUU, por el alto riesgo de asociación con esas patologías (16).…”

Section: Discussionunclassified

“…También pueden presentarse anormalidades cromosómicas, tanto aneuploidías como trisomías 18 y 13 (7,8,9,10). La trisomía 21 se asocia con mucho menor frecuencia con AUU (4).…”

Section: Introductionunclassified

Incidencia Y Asociaciones De Arteria Umbilical Única en Recién Nacidos: Maternidad Del Hospital Clínico De La Universidad De Chile, 1998-2010

Jarpa

2011

Rev. chil. obstet. ginecol.

Self Cite

View full text Add to dashboard Cite

RESUMENAntecedentes: La presencia de 2 vasos en el cordón umbilical es una anomalía con incidencia de 1% de todos los recién nacidos. Se asocia frecuentemente con restricción del crecimiento intrauterino (RCIU), malformaciones estructurales mayores y cromosómicas y prematuridad. Constituye un factor de riesgo que aumenta la mortalidad fetal tardía y neonatal. Objetivos: Establecer la prevalencia al nacimiento de arteria umbilical única (AUU), la magnitud de las asociaciones con malformaciones congénitas (MFC), RCIU, prematuridad y su influencia en la morbimortalidad neonatal. Método: Se usó la base de datos que el Estudio Colaborativo Latino Americano de Malformaciones Congénitas (ECLAMC) tiene en la maternidad del Hospital Clínico de la Universidad de Chile. Incluyó a todos los recién nacidos vivos (RN) y mortinatos con peso de nacimiento 500 gramos o más en el período mayo 1998 a junio 2010. Se comparó algunas variables demográficas entre los casos y sus controles. Resultados: En 22.011 nacimientos ocurridos hubo 65 RN con AUU (0,3%), 9 eran mortinatos (13,8%), 88,9% de ellos presentaban RCIU. Eran prematuros 55,4% de los RN. El 60% de los casos de AUU estaban asociados a MFC mayores, destacando las del aparato genitourinario (35,3%) y las cardiovasculares (29,4%); 23,8% eran parte de un síndrome, donde dominaban la trisomía 13 y 18 (12 casos, 18,5%). De los RN vivos fallecieron 13 (23,2%), 8 (61,5%) presentaban RCIU. Conclusión: La AUU es un factor de alto riesgo de asociación con RCIU, MFC mayores estructurales y/o cromosómicas, prematuridad y de un aumento de la morbimartalidad neonatal. PALABRAS CLAVE: Arteria umbilical única, malformaciones congénitas SUMMARYBackground: The presence of only two blood vessels in the cord blood is a congenital anomaly that has an incidence about 1% among all newborns. Frequently, it is associated with intrauterine growth restriction (IUGR), major congenital malformations (MCMF), chromosome anomalies and prematurity. It represents a risk factor that increases late foetal and neonatal mortality and morbidity. Aims: To estimate the prevalence at birth of unique umbilical artery (UUA), to know its association with congenital anomalies, IUGR, prematurity and to evaluate its influence in neonatal morbidity and mortality. Methods: We studied data registered in the Latin American Study of Congenital Malformations (ECLAMC) from the Maternity of the Clinical Hospital of University of Chile from May 1998 and June 2010. All newborns (alive and stillbirths) with a birth weigh

show abstract

Artéria umbilical única - Relato de caso

Sabino¹,

Klein²,

Fernandes³

et al. 2018

Rev Ped SOPERJ

View full text Add to dashboard Cite

Artéria umbilical única; Anormalidades congênitas; Relações materno-fetais. Resumo Introdução: apresentamos um caso de artéria umbilical isolada, que, embora seja um achado visto frequentemente ao exame ultrassonográfico pré-natal e nas salas de parto, pode estar associado a outras malformações congênitas. Objetivo: relatar um caso de artéria umbilical única. Descrição do caso: apresentamos um caso de artéria umbilical isolada em um recém-nascido a termo, sem repercussões maternas ou fetais detectáveis. Discussão: a presença de artéria umbilical única pode estar associada a outras malformações congênitas. Na presença de fatores de risco, tais como idade avançada, alterações genéticas, diabetes mellitus durante a gravidez, história familiar de doença cardíaca congênita ou inseminação artificial, deverá ser realizado aconselhamento genético, ecocardiografia e ultrassonografia abdominal e geniturinária.

show abstract

Arteria umbilical única y malformaciones asociadas: Experiencia en el Hospital Clínico de la Universidad de Chile

Cited by 3 publications

References 8 publications

Single Umbilical Artery and Associated Malformations in over 5500 Autopsies: Relevance for Perinatal Management

Single Umbilical Artery and Associated Malformations in over 5500 Autopsies: Relevance for Perinatal Management

Incidencia Y Asociaciones De Arteria Umbilical Única en Recién Nacidos: Maternidad Del Hospital Clínico De La Universidad De Chile, 1998-2010

Artéria umbilical única - Relato de caso

Contact Info

Product

Resources

About