Arterial Oxygenation During One-Lung Anaesthesia (2)

Khanam, Tina; Branthwaite, M. A.

doi:10.1097/00132586-197402000-00021

Cited by 2 publications

(3 citation statements)

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“…Although other indices can be used to access pulmonary oxygen exchange, apart from invasive measurement of venous admixture [19], none has been shown to provide a true picture of pulmonary oxygen exchange. We propose that the above method of calculating PIO 2 -PcO 2 difference gives a more complete description of oxygen exchange during thoracotomy and, compared with other methods [22][23][24], has the added advantage of being noninvasive.…”

Section: Discussionmentioning

confidence: 99%

A noninvasive method for evaluating the effect of thoracotomy on shunt and ventilation perfusion inequality

1997

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SummaryA new noninvasive method was used to evaluate gas exchange in 12 patients undergoing thoracotomy for a variety of surgical procedures. A plot of inspired oxygen partial pressure versus oxygen saturation was analysed to calculate the independent contribution of shunt and intermediate ventilation/perfusion ratio which occurs during general anaesthesia for thoracotomy. A model based on the inspired to arterial oxygen difference involving the shunt equation was used to show how the relationship between inspired oxygen partial pressure and oxygen saturation could be used to derive two parameters of oxygen exchange, the virtual shunt and an index of low ventilation/perfusion ratio. In all cases, there was a very good fit of the data to the model. Thoracotomy caused a mean increase in shunt from 13.8% to 20.8% and a worsening ventilation/ perfusion ratio from 0.5 to 0.2, the magnitude of which depended on the underlying pathology. In two patients, the ventilation/perfusion ratio decreased to less than 0.1. The method enables the prediction of oxygen saturation at different inspired oxygen partial pressures and allows the two components of gas exchange to be isolated using simple routine measurements of inspired oxygen and pulse oximetry.

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Section: Discussionmentioning

confidence: 99%

A noninvasive method for evaluating the effect of thoracotomy on shunt and ventilation perfusion inequality

1997

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“…This may be due to having fewer number of females during the study period and larger number will be required to present this evidence as conclusive. The mean pre-operative PaO2 in smoker was 89.98 mmHg and non-smoker was 94.10 mmHg and PaO2 at 25 minutes also showed a higher PaO2 in smokers (Table No. 5). This study has shown a significant negative correlation in the smokers.…”

Section: Discussionmentioning

confidence: 48%

“…This study was an attempt to find out the predictive factors for decreasing PaO2 and to find out if it was possible to predict which patient will have a clinically important decrease of PaO2 during OLA for thoracic surgery based on these factors. 5,6,7 Objectives of the study are to find out the potential factors that reduce arterial oxygenation (PaO2) during One Lung Anaesthesia (OLA) and to find out the possibility of predicting the PaO2 during One Lung Anaesthesia (OLA) based on these potential factors.…”

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confidence: 99%