Arterial thrombosis in Crohn's disease

Halliday, Craig E.W.; Farthing, M. J. G.

doi:10.5694/j.1326-5377.1988.tb120770.x

Cited by 18 publications

(6 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In concordance with these reports, an observational study reported a 4‐fold increased risk of venous thromboembolism for patients with CD as compared with the general population 5. Case reports of ischemic stroke in unusually young patients with CD indicate that a similar association may exist with respect to cerebrovascular events2, 6–12 but observational data are lacking. One recent study reported a slightly increased risk of cerebrovascular disease in patients with CD (incidence rate ratio 1.32; 95% confidence interval [CI] 1.05–1.66)13; however, that study lacked power to investigate acute ischemic stroke as a separate outcome and did not adjust for several important cerebrovascular risk factors such as smoking, obesity, hypertension, atrial fibrillation, or drug intake known to be associated with an increased or decreased risk of stroke.…”

mentioning

confidence: 99%

Risk of ischemic stroke in patients with Crohnʼs disease

Andersohn

Waring²,

Garbe

2010

Inflammatory Bowel Diseases

View full text Add to dashboard Cite

show abstract

mentioning

confidence: 99%

Risk of ischemic stroke in patients with Crohnʼs disease

Andersohn

Waring²,

Garbe

2010

Inflammatory Bowel Diseases

View full text Add to dashboard Cite

show abstract

“…3 These events include primary thromboses of retinal or cerebral arteries, and arteries of the upper and lower limbs with significant morbidity and mortality. 4–13…”

mentioning

confidence: 99%

Aortic Mural Thrombi in Patients With Inflammatory Bowel Disease

Novacek¹,

Haumer²,

Schima³

et al. 2004

Inflammatory Bowel Diseases

View full text Add to dashboard Cite

Thromboembolic events are a known complication in inflammatory bowel disease (IBD). We report on 2 young women with IBD and aortic mural thrombi as a source of arterioarterial embolization to the lower limbs resulting in significant morbidity. The first case was a 36-year-old woman with severe ulcerative colitis who presented with signs of microembolism into two toes of her right foot. A thrombus in the otherwise normal infrarenal aorta with occlusion of the inferior mesenteric artery was revealed by computed tomography (CT) and intrarterial angiography. The digital ischemia resolved without sequelae. The second case was a 41-year-old woman with Crohn's disease complicated by fistulas. She developed acute ischemia of her right leg. Arteriography and CT revealed infrapopliteal embolic occlusions and a thrombus in the distal otherwise normal abdominal aorta and the left iliac artery. A primarily successful thrombectomy had to be repeated 5 times because of reocclusion. Eventually the leg was exarticulated at the knee. In both patients no further thromboembolic event occurred during follow-up of 4 1/2 years and 5 1/2 years, respectively, and aortic thrombi had resolved at follow-up CT scans. Extensive work up for hypercoagulability was negative in both patients. We consider IBD as the most likely trigger for arterioarterial embolization in the absence of thrombophilia in both patients. Finally we give an overview of the literature of similar cases with aortic mural thrombi in IBD patients.

show abstract

“…Vascular involvement in Crohn disease is rare and has been reported in association with concomitant thromboembolic disease, polyarteritis nodosa, and Takayasu's arteritis (TA) [9][10][11][12][13][14]. Both polyarteritis nodosa and TA may involve the renal arteries and present with severe hypertension due to the renal artery stenosis [15][16][17][18].…”

Section: Discussionmentioning

confidence: 99%

Renal artery stenosis associated with Crohn disease

Kuzmić¹,

Kolaček²,

Brkljačić

et al. 2001

Pediatric Nephrology

View full text Add to dashboard Cite

Although extraintestinal complications involving skin, joints, eyes and liver are common in children with inflammatory bowel disease, hypertension is rare. We report data from a 16-year-old boy with renovascular hypertension and Crohn disease. To our knowledge, a patient with renal artery stenosis associated with Crohn disease has not been previously reported. Possible causes of renal vascular lesion in Crohn disease are discussed.

show abstract

Arterial thrombosis in Crohn's disease

Cited by 18 publications

References 22 publications

Risk of ischemic stroke in patients with Crohnʼs disease

Risk of ischemic stroke in patients with Crohnʼs disease

Aortic Mural Thrombi in Patients With Inflammatory Bowel Disease

Renal artery stenosis associated with Crohn disease

Contact Info

Product

Resources

About