Arteriolar Resistance and Hemorheological Disorders Related to Raynaud's Phenomenon

Mchedlishvili, G. I.; Mantskava, Maia; Pargalava, Nugzar

doi:10.1006/mvre.2001.2335

Cited by 5 publications

(5 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…For example, an increase in the RBC aggregation index is suggested as a predictor of coronary artery disease. [20][21][22][23][24][25][26][27][28][29][30] In the present study, blood rheological parameters were studied in patients with AF for the first time in Georgia using the innovative and widely acknowledged "Georgian technique" for the assessment of red blood cell (RBC) aggregability. [20][21][22][23][24][25][26][27][28][29][30] We discovered a link between the progression of AF and negative changes in blood rheological parameters.…”

Section: Discussionmentioning

confidence: 99%

“…[20][21][22][23][24][25][26][27][28][29][30] In the present study, blood rheological parameters were studied in patients with AF for the first time in Georgia using the innovative and widely acknowledged "Georgian technique" for the assessment of red blood cell (RBC) aggregability. [20][21][22][23][24][25][26][27][28][29][30] We discovered a link between the progression of AF and negative changes in blood rheological parameters. As is well known, hemorheological and hemodynamic factors play a crucial role in the maintenance of optimal perfusion and proper function of the myocardium as well as any other tissue.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Rheological Changes During the Atrial Fibrillation

Gotsadze¹,

Kandashvili²,

Momtselidze³

et al. 2023

Georgian Biomedical News

View full text Add to dashboard Cite

BACKGROUNDAccording to recent estimates atrial fibrillation (AF) affects approximately 1% of the global population with the tendency to grow over the next 50 years. Despite significant advances in the diagnosis and management of AF, it remains one of the biggest challenges for modern medicine. OBJECTIVES To better understand of pathological processes underlying AF, we aimed to access relations between hemodynamic and rheological properties of blood in patients with different forms of AF. METHODS The erythrocyte (RBC) aggregation index (EAI), erythrocyte (RBC) deformability index EDI), and plasma viscosity (Vpl) were measured in 70 patients with AF and 20 healthy individuals using a textural analysis system (Tas-Plus, Leitz, Germany) and innovative "Georgian technique" with the unique function of a quantitative assessment of the RBC aggregation index. RESULTSThe mean erythrocyte (RBC) aggregation index (EAI), erythrocyte (RBC) deformability index (EDI), and plasma viscosity (PV) were statistically higher in patients with paroxysmal, persistent, and permanent AF compared to the healthy controls; however, there were no significant differences between different groups of patients with AF. CONCLUSIONS The findings of our investigation lead us to believe that disturbances in the hemorheological system play a crucial role in the pathogenesis of AF. These suggest that RBC aggregation is an essential factor in the progression of AF and requires constant monitoring for early prevention and adequate management of the disease. KEYWORDS Atrial fibrillation (AF); erythrocyte (RBC) aggregation index (EAI); erythrocyte (RBC) deformability index (EDI); hemorheology; plasma viscosity (PV).

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Rheological Changes During the Atrial Fibrillation

Gotsadze¹,

Kandashvili²,

Momtselidze³

et al. 2023

Georgian Biomedical News

View full text Add to dashboard Cite

show abstract

“…The improvement of capillary blood flow during therapy with the original L-ornithine-L-aspartate is also evidenced by the results of capillaroscopy of the bulbar conjunctiva and the nail bed, according to which, with the introduction of the drug, there was an increase in the velocity and homogenization of blood flow, a significant decrease in stagnation in the capillaries. The improvement in hemorheological parameters led to a decrease in the intravascular conjunctival index [7,8].…”

Section: Discussion Discussionmentioning

confidence: 99%

“…Clinical examination of patients was carried out in accordance with accepted diagnostic standards. The functional state of the endothelium sc e NIWA by laser Doppler flowmetry (LDF) for dual laser Doppler flowmetry [7].…”

Section: Methodsmentioning

confidence: 99%

Hepatoprotective Therapy for Disease and Diabetes

2021

bmms

View full text Add to dashboard Cite

Our work is devoted to the treatment of non-alcoholic fatty liver disease as a complication in patients with complex cardiovascular pathology and type 2 diabetes mellitus. The data of the study of the effect of the drug HepaMerz® on the functional state of the liver, endothelium, rheological properties of blood, the state of capillary blood fl ow, markers of end toxicosis and clinical state in this category of patients are presented. The results obtained confirm the possibility of using the drug HepaMerz® for liver functional disorders in patients with cardiovascular diseases and complex type 2 diabetes mellitus.

show abstract

“…Following the Helsinki convection about scientific research, the participants were informed about the inclusion of the depersonalized method in the study, an informed consent was drawn up, which was signed by all volunteers included in the study addition to measuring the functional state of resistive arteries, we investigated the intravascular state of the blood, which forms the flow laminarity, or its turbulence [8]. Specifically, we measured the rate of erythrocyte aggregation [9], the rate of erythrocyte deformability in [10], plasma viscosity according to existing certified techniques [11].…”

Section: Methods Methodsmentioning

confidence: 99%

Investigation of Microcirculatory in Resistive Arteries

2021

bmms

View full text Add to dashboard Cite

Тhe article shows the physiological signifi cance of resistive arteries in relation to blood fl ow. The article describes a new non-invasive method for assessing the functional state of resistive arteries, which indicates the resistance of resistive arteries. Microcirculation coeffi cient – resistance of resistive arteries is an easy-to-use diagnostic method for assessing circulatory problems. The article shows new normative indicators of the microcirculation index in young healthy men. And also shows the rheological indicators for the same group.

show abstract

Arteriolar Resistance and Hemorheological Disorders Related to Raynaud's Phenomenon

Cited by 5 publications

References 9 publications

Rheological Changes During the Atrial Fibrillation

Rheological Changes During the Atrial Fibrillation

Hepatoprotective Therapy for Disease and Diabetes

Investigation of Microcirculatory in Resistive Arteries

Contact Info

Product

Resources

About