A 70 yr old male was admitted to a nephrology department with an acute anuric renal failure. In his past history, one could note a hypertensive cardiomyopathy with an atrial fibrillation, treated with amiodarone, digoxine, flecainide, trinitrine and fluindione, and a noninsulin dependent diabetes treated with metformine. One month before admission, the patient had been treated for an ischaemic cerebrovascular stroke, which was complicated by a rhabdomyolysis responsible for renal failure with a creatinine clearance measured at 26 mL·min -1 .On admission, clinical examination revealed an overall cardiac failure and fine crackles were heard over the pulmonary bases. Oedema of the lower limbs was also found. Biological analysis revealed a worsening of the pre-existing renal failure with a creatinine clearance of 9 mL·min -1 without any associated ionic disorder. Diuretic treatment was initiated, enabling a transitory improvement before a rapid deterioration of the renal function occurred. The patient developed anuria, so that dialysis became necessary. The anticoagulant treatment was interrupted and treatment with heparin injections (250 IU·kg -1 ·day -1 in three injections) was initiated, 4 days before a dialysis catheter was set up. Injections immediately before and immediately after the venous catheterization were omitted. The prothrombin time was then measured at 96% and the activated