Arteriovenous malformation underlying a plexiform neurofibroma: An unusual presentation

Abstract

Vascular abnormalities associated with neurofibromatosis type 1 are well described in the literature, however, arteriovenous malformation is a very rare finding in neurofibromatosis type 1. We report the case of an 11-year-old girl who presented with a soft mass on the right flank. Provisional diagnosis of plexiform neurofibroma was made on the basis of clinical and histological observations. Because the lesion was warm on palpation, imaging studies were performed to evaluate further and arteriovenous malformation was detected underlying the plexiform neurofibroma. This report emphasizes the importance of careful examination and proper investigations of the plexiform neurofibroma prior to treatment strategies to avoid future complications. The rarity of plexiform neurofibroma in association with arteriovenous malformation at the same site was also highlighted in this report.

Neurofibromatosis type – 1 (NF-1) presenting as intracerebral haemorrhage in a young adult- unveiling a rare culprit

“…Neurofibromatosis is usually a benign condition but it can sometimes have potentially life threatening squeale. One such sequalae is vasculopathy especially in the nervous system (Abbas et al, 2017;Singh et al, 2021). These vasculopathies range from stenosis, aneurysms, malformations, ruptures to even fistula formation.…”

Hemorragia digestiva como manifestación de neurofibromatosis tipo I: reporte de un caso

“…Las alteraciones gastrointestinales en la NF1 se clasifican en dos grandes grupos: tumores o alteraciones vasculares. En algunas ocasiones y debido a su naturaleza hipervascular, los neurofibromas se suelen confundir con alguna malformación vascular (16,17) . La mayoría de estas lesiones son asintomáticas; las tumoraciones pueden producir cuadros de obstrucción intestinal, hemorragia digestiva por compresión vascular mecánica e incluso ictericia obstructiva, mientras que las alteraciones vasculares se deben sospechar ante la presencia de hemorragia digestiva, principalmente rectorragia (7) .…”