Arthritic Conditions Affecting the Temporomandibular Joint

Mercuri, Louis G.; Abramowicz, Shelly

doi:10.1007/978-3-319-28100-1_32-2

Cited by 3 publications

(4 citation statements)

References 114 publications

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“…OA is considered a disease of the bone, cartilage, and supporting tissues resulting from a combination of biologic and mechanical processes that decrease the turnover of subchondral bone and articular cartilage resulting in degeneration of cartilage with subsequent osseous erosion, sclerosis, and osteophyte formation seen at the margins (5,7,8). Most patients with early-stage disease can be successfully managed non-surgically and/or with minimally invasive procedures (6,(9)(10)(11). Idiopathic condylar resorption (ICR) is also a low-inflammatory condition but of unknown etiology.…”

Section: Types Of Tmj Arthritis Low-inflammatory Arthritic Conditionsmentioning

confidence: 99%

“…These systemic disorders are well known with examples such as rheumatoid arthritis (RA), ankylosing spondylitis (AS), psoriatic arthritis (PA) and juvenile idiopathic arthritis (JIA) and metabolic arthritis (MA) (such as gout, pseudogout etc.) (10). The TMJs could potentially be affected by any of these conditions, and to varying incidence and severity (12).…”

Section: High-inflammatory Arthritic Conditionsmentioning

confidence: 99%

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Arthritic diseases: an indication for alloplastic temporomandibular joint replacement

Renapurkar¹,

Mehra²

2023

Front Oral Maxillofac Med

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Arthritic disease or degenerative joint disease (DJD) affecting the temporomandibular joints (TMJs) has the potential to cause degeneration of soft and hard tissues secondary to inflammation leading to significant dysfunction, pain and deformity. Low and high-inflammatory varieties of arthritic diseases have different pathophysiology, clinical course and prognosis. While low-inflammatory arthritic conditions such as osteoarthritis (OA) are more common in older age, high-inflammatory conditions can affect younger individuals. Accurate diagnosis forms the basis of timely and appropriate management. Many patients if diagnosed early, can often be managed with conservative non-surgical and/or minimally invasive surgical modalities. Severe or late-stage arthritic involvement of the TMJ can cause significant loss of bone volume with resultant dentofacial deformity, malocclusion and/or ankylosis. Such conditions may require reconstruction of the condyle with either autogenous or alloplastic options. Autogenous options such as costochondral grafts have fallen out of favor but may be a viable option for use in skeletally immature patients due to potential for growth. Based on current evidence, alloplastic total joint reconstruction with a stock or patient-fitted prosthesis is the most predictable treatment option with least risk of re-ankylosis, no donor site morbidity and allowing earlier return to function with long-term stability. This chapter will focus on common low-and high-inflammatory arthritic conditions that affect the TMJs and should be considered indications for alloplastic TMJ reconstruction.

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Section: Types Of Tmj Arthritis Low-inflammatory Arthritic Conditionsmentioning

confidence: 99%

Section: High-inflammatory Arthritic Conditionsmentioning

confidence: 99%

Arthritic diseases: an indication for alloplastic temporomandibular joint replacement

Renapurkar¹,

Mehra²

2023

Front Oral Maxillofac Med

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“…17,18 Comorbid diseases which may specifically affect the TMJ include: rheumatoid arthritis, juvenile idiopathic arthritis, psoriatic arthritis, systemic lupus erythematosus, osteoarthritis and neoplasia. 19 While the incidence rate of TMD is only slightly greater in women than men, up to four times as many women seek treatment in addition to having a greater overall pain sensitivity. TMD is also more likely to persist in women.…”

Section: Risk Factors For Developing Tmdmentioning

confidence: 99%

Temporomandibular Disorder: a practical guide for dental practitioners in diagnosis and management

Beaumont

Garg

Gokhale

et al. 2020

Australian Dental Journal

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Temporomandibular disorder is a broad term encompassing pain and/or dysfunction of the masticatory musculature and the temporomandibular joints. Pain arising from a temporomandibular disorder is a common reason for seeking dental care. It is essential that dental practitioners are able to accurately diagnose and manage this condition. Identifying people at highest risk of developing a temporomandibular disorder and knowing which procedures are more likely to initiate or exacerbate a temporomandibular disorder, are important to reduce the likelihood of its acute and chronic presentation. The aim of this paper is to provide the dental practitioner with a clinical guideline for reference including practical tools to examine, diagnose and manage patients with temporomandibular disorder. In addition the risk profile of patients and procedures is explored to help minimize the occurrence of temporomandibular disorders and mitigate its symptoms. The scope of the dental practitioner in the management of acute and chronic temporomandibular disorders is presented, with guidance about when referral to a specialist is indicated.

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“…Arthritic diseases are the most common join disorders, comprising 100 to 150 rheumatic conditions. These diseases have multifactorial etiology such as traumatism in osteoarthritis, immunological factors in RA, and metabolic disorders in gout 1 , 2 . RA is an autoimmune disease with highly debilitating potential, common in an aging society, with a prevalence in women.…”

Section: Introductionmentioning

confidence: 99%

cis-Aconitic Acid, a Constituent of Echinodorus grandiflorus Leaves, Inhibits Antigen-Induced Arthritis and Gout in Mice

et al. 2021

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cis-Aconitic acid is a constituent from the leaves of Echinodorus grandiflorus, a medicinal plant traditionally used in Brazil to treat inflammatory conditions, including arthritic diseases. The present study aimed to investigate the anti-arthritic effect of cis-aconitic acid in murine models of antigen-induced arthritis and monosodium urate-induced gout. The possible underlying mechanisms of action was evaluated in THP-1 macrophages. Oral treatment with cis-aconitic acid (10, 30, and 90 mg/kg) reduced leukocyte accumulation in the joint cavity and C-X-C motif chemokine ligand 1 and IL-1β levels in periarticular tissue. cis-Aconitic acid treatment reduced joint inflammation in tissue sections of antigen-induced arthritis mice and these effects were associated with decreased mechanical hypernociception. Administration of cis-aconitic acid (30 mg/kg p. o.) also reduced leukocyte accumulation in the joint cavity after the injection of monosodium urate crystals. cis-Aconitic acid reduced in vitro the release of TNF-α and phosphorylation of IκBα in lipopolysaccharide-stimulated THP-1 macrophages, suggesting that inhibition of nuclear factor kappa B activation was an underlying mechanism of cis-aconitic acid-induced anti-inflammatory effects. In conclusion, cis-aconitic acid has significant anti-inflammatory effects in antigen-induced arthritis and monosodium urate-induced arthritis in mice, suggesting its potential for the treatment of inflammatory diseases of the joint in humans. Additionally, our findings suggest that this compound may contribute to the anti-inflammatory effect previously reported for E. grandiflorus extracts.

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Arthritic Conditions Affecting the Temporomandibular Joint

Cited by 3 publications

References 114 publications

Arthritic diseases: an indication for alloplastic temporomandibular joint replacement

Arthritic diseases: an indication for alloplastic temporomandibular joint replacement

Temporomandibular Disorder: a practical guide for dental practitioners in diagnosis and management

cis-Aconitic Acid, a Constituent of Echinodorus grandiflorus Leaves, Inhibits Antigen-Induced Arthritis and Gout in Mice

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