Arthritis and non‐antibiotic‐associated pseudomembranous colitis

Abstract

LETTERS 1075numbers of patients studied. However, if the numbers of patients from various studies are pooled, as shown by Baer et a1 (2), then there is no difference between slow and fast acetylators in SLE patients and control subjects. This finding, of course, is different from that seen in many patients with drug-related lupus.In one particular study from my laboratory (3), we showed a difference in acetylator phenotype between white SLE patients (71% slow acetylators) and black SLE patients (58% slow acetylators). This result reflects the clinical observations in the US, that drug-related lupus occurs more frequently in white subjects than in black subjects.I agree with Sardas and coworkers' other conclusions, and would point out that more and better data in different population groups and different racial groups are needed.

Joint Manifestations in Gastrointestinal Diseases

“…The articular manifestations often occur at the height of the colitic involvement [164. 165], usually beginning 2-5 weeks after the onset of diarrhea and remitting within 1-2 weeks of treating the PMC [ 173]. Recently, PMC asso ciated with arthritis was reported in a 28-yearold pregnant female who denied the recent use of antibiotics [ 173].…”