Background: This retrospective study aimed to report the prevalence and predisposing factors affecting subscapularis muscle atrophy and fatty infiltration (MAFI) in patients without a subscapularis tear identified through arthroscopy and to analyze the effect of this condition on surgical outcomes.Methods: Between 2020 and 2022, 153 patients (mean age 58.1±10.2 years; 84 men and 69 women) who underwent repair of posterosuperior cuff tears with no subscapularis tear identified during arthroscopy were retrospectively analyzed. Baseline characteristics, preoperative and follow-up (6 months) magnetic resonance imaging (MRI) findings, arthroscopic findings, and clinical outcomes (>1 year) were recorded. Results: The prevalence of subscapularis MAFI (Goutallier grade 1 or 2) was 73.9% (113/153), of which the prevalence of Goutallier grade 2 was 23.5% (36/153). From multivariable logistic regression analysis, female sex (odds ratio [OR], 5.6; 95% CI, 1.7–18.6; P=0.005), older age (OR, 1.1; 95% confidence interval, 1.0–1.1; P=0.052), advanced supraspinatus MAFI by Goutallier grade (OR, 3.2; 95% CI, 1.5–6.9; P=0.004), and synovitis (OR, 2.8; 95% CI, 1.1–7.9; P=0.030) were independent predisposing factors for subscapularis MAFI. However, patients with preoperative subscapularis MAFI exhibited similar final (1 year) range of motion, pain levels, functional scores, and belly press strength ratios (median, 0.84; interquartile range [IQR], 0.77–0.94] vs. 0.82; IQR, 0.73–0.90; P=0.297) compared to those without preoperative subscapularis MAFI.Conclusions: Although the study's retrospective design and the inclusion of only surgical patients with isolated small to medium supraspinatus tears limit its generalizability, subscapularis MAFI on Y-view MRI is frequently observed even in the absence of subscapularis tear among patients undergoing posterosuperior rotator cuff (RC) repair. This could be affected by supraspinatus MAFI, female sex, older age, and synovitis during surgery. However, because subscapularis MAFI does not affect the outcome of RC repair, surgeons need not be concerned about such occurrences without a tear when repairing small to medium posterosuperior RC tear.Level of evidence: IV.