Arthroscopic treatment of Mycobacterium massiliense septic arthritis outbreak after intra-articular injection

Lee, Byung Ill; Jang, Byung-Woong; Choi, Hyung Suk; Lee, Jeong Seok; Kim, Yong Beom

doi:10.1097/md.0000000000023839

Cited by 2 publications

(1 citation statement)

References 32 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Infection following ACL reconstruction has been reported in up to 2.6% of cases 14 . Recent data have indicated increasing recognition of NTM infection in orthopaedic surgery, including after peri-articular injections and in periprosthetic joint infection 15 , 16 . NTM infection has been associated with environmental exposure, and water is a common mode of transmission.…”

Section: Discussionmentioning

confidence: 99%

A Systematic Review of Nontuberculous Mycobacterium Infection Following Anterior Cruciate Ligament Reconstruction

et al. 2023

View full text Add to dashboard Cite

Background:Although infection following anterior cruciate ligament (ACL) reconstruction is rare, these cases have potentially catastrophic ramifications. Nontuberculous mycobacteria (NTM) are ubiquitous, located in the water supply and soil. Our objective was to review the literature to characterize NTM infection following ACL reconstruction.Methods:A database search was performed for arthroscopic ACL reconstructions that resulted in a postoperative diagnosis of NTM infection.Results:The literature search returned 6 case reports that met the inclusion criteria. The initial postoperative presentation occurred after 3 to 52 weeks, which is consistent with reports of postoperative NTM infection.Conclusions:The common indolent course of NTM infection hinders prompt diagnosis and treatment. Organism susceptibility testing is crucial for effective treatment and limiting unnecessary antibiotic exposure.Clinical Relevance:The duration of medical treatment for NTM infection is 4 to 6 months, depending on the severity of disease and species. Based on the aggregate literature, we recommend removal of local implants if the infection is localized and without articular involvement. However, in cases of articular involvement, all fixation and graft material should be removed.

show abstract

Section: Discussionmentioning

confidence: 99%

A Systematic Review of Nontuberculous Mycobacterium Infection Following Anterior Cruciate Ligament Reconstruction

et al. 2023

View full text Add to dashboard Cite

show abstract

<i>Mycobacterium abscessus</i> as a causative agent of periprosthetic infection

Kasimova,

Kochish,

Gordina

et al. 2023

jour

View full text Add to dashboard Cite

Introduction Mycobacterium abscessus species belongs to the group of non-tuberculosis mycobacteria responsible for chronic infections in people with weakened immunity. M. abscessus exist in various ecological niches and are able to colonize artificial surfaces, including medical and surgical instruments/ devices. Due tothe low incidence of M. abscessus as a causative agent of orthopedic infection, a rare clinical case of periprosthetic infection caused by M.abscessus would interest practitioners.The aim is to present a clinical case of periprosthetic infection caused by M. abscessus.Materials and methods From the medical records and discharge documents, it was known that female patient X. underwent total hip replacement at her residence hospital. Signs of acute infection of the postoperative wound appeared in the early postoperative period.Results Three months later, the patient was hospitalized in a specialized institution with a diagnosis of chronic deep periprosthetic infection. During the examination, the mycobacterial etiology of the process was established. During two hospitalizations, the patient underwent 4 consecutive revision surgeries (including muscle plastic surgery and installation of an antimicrobial spacer) and massive parenteral antibiotic therapy for 8 months, including at the outpatient stage, using at least 3 antibacterial agents. After 4 years, the patient does not complain of the infectious process. Postoperative scar is 45 cm. The residual shortening of the right lower limb of 3 cm was compensated by orthopedic shoes.Discussion Treatment of infection caused by M. abscessus is challenging due to the natural resistance of the pathogen to a wide range of antibacterial drugs. The literature describes separate cases of orthopedic infections caused by this pathogen. All authors agree that the key to successful treatment is a combination of radical surgical debridement and antibacterial therapy using at least three antimicrobial drugs.Conclusion A rare clinical case of periprosthetic infection caused by Mycobacterium abscessus after primary hip replacement is presented. This infectious agent is a rare pathogen, for which there is no proven therapeutic algorithm. Long-term aggressive antibiotic therapy in combination with stage-by-stage surgical treatment was successful.

show abstract

Arthroscopic treatment of Mycobacterium massiliense septic arthritis outbreak after intra-articular injection

Cited by 2 publications

References 32 publications

A Systematic Review of Nontuberculous Mycobacterium Infection Following Anterior Cruciate Ligament Reconstruction

A Systematic Review of Nontuberculous Mycobacterium Infection Following Anterior Cruciate Ligament Reconstruction

<i>Mycobacterium abscessus</i> as a causative agent of periprosthetic infection

Contact Info

Product

Resources

About