Articles in<i>Endocrinology and Metabolism</i>in 2016

Lee, Won Young

doi:10.3803/enm.2017.32.1.62

Cited by 3 publications

(3 citation statements)

References 61 publications

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“…To maintain healthy conditions while losing weight and reducing body fat, especially visceral fat, improving the metabolic profile such as blood glucose levels, blood pressure, and endothelial cell function is important. 17 SGLT-2 inhibitors are a class of glucoselowering drugs with proven efficacy for lowering the risk of cardiovascular events in patients with T2DM. In a large-scale pooled analysis assessing the effects of SGLT-2 inhibitors on cardiovascular outcomes, there was an improvement in MACE (the composite of cardiovascular death, myocardial infarction, or stroke) among patients with previous ASCVD.…”

Section: Discussionmentioning

confidence: 99%

Effects of 6 Months of Dapagliflozin Treatment on Metabolic Profile and Endothelial Cell Dysfunction for Obese Type 2 Diabetes Mellitus Patients without Atherosclerotic Cardiovascular Disease

Hong

Park

Kim

et al. 2020

Journal of Obesity & Metabolic Syndrome

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Background: Sodium-glucose cotransporter 2 inhibitors reduce the risk of cardiovascular death in individuals with type 2 diabetes mellitus (T2DM) and cardiovascular disease, but the effect of these inhibitors on early cardiovascular disease remains unknown. This study evaluated the effect of dapagliflozin on the metabolic profiles and endothelial cell function in obese patients with T2DM without established cardiovascular disease. Methods: We enrolled 140 patients with a mean age, weight, and body mass index (BMI) of 47 years, 83 kg, and 30.3 kg/m 2 , respectively. Dapagliflozin (10 mg daily for 6 months) was administered to obese patients with T2DM without established cardiovascular disease. Participants' weight, BMI, body fat mass (BFM), muscle mass, glycosylated hemoglobin (HbA1c), lipid profile, waist to hip ratio (WHR), and pulse wave velocity (PWV) were measured at baseline and after 6 months. Results: Participants experienced statistically significant reductions in their HbA1c, fasting plasma glucose, lowdensity lipoprotein cholesterol, total cholesterol, body weight, BMI, WHR, BFM, and aortic PWV, without a significant change in their muscle mass, extracellular fluid, or intracellular volume. Statistically significant reductions in aortic PWV were associated with a decrease in BFM, visceral fat, WHR, and homeostatic model assessment of insulin resistance. Conclusion: Dapagliflozin may be beneficial in preventing early cardiovascular disease in obese patients with T2DM without established cardiovascular disease.

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Section: Discussionmentioning

confidence: 99%

Effects of 6 Months of Dapagliflozin Treatment on Metabolic Profile and Endothelial Cell Dysfunction for Obese Type 2 Diabetes Mellitus Patients without Atherosclerotic Cardiovascular Disease

Hong

Park

Kim

et al. 2020

Journal of Obesity & Metabolic Syndrome

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“…One should consider utilizing appropriate buffers depending on the outcome of the experiment. Often protein extracts obtained from tissue are dilute demanding for necessary enrichment procedures to prolong the shelf life and precipitation procedures help to make the proteins more stable [53].…”

Section: Incomplet E Transfermentioning

confidence: 99%

Review on Human Placental Proteomics

Shetty¹,

Hegde²,

Anbu³

et al. 2022

ECS Trans.

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The human placenta plays a crucial part during conception of another human life. Through this time the placenta forms and grows along with the fetus and removed after the birth of the child. The human placenta is rich in proteins and other nutrients required for the growth of the fetus is now discarded. The proteins present in the placenta is studied by extracting proteins from the spongy tissue or by growing the cells in culture media. Use of appropriate technique is also essential in case of diagnosis of pathological condition or to use these proteins as potent drug. This paper reviews the basic components of the placenta and proteomic techniques used in various studies for normal and pathological conditions in the human placenta.

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“…In humans, this process entails maintaining the homeostasis of electrolytes, gases, and nutrients [2,3], in which the endocrine system plays a critical role. The endocrine system is a chemical messenger system that consists of receptors and feedback loops mediated by hormones released from different glands into the circulatory system to regulate a target organ [4][5][6].…”

Section: Introductionmentioning

confidence: 99%

Insulin Resistance and Glucose Metabolism during Infection

Arneth

2023

Endocrines

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Specific critical functions of endocrine and immune cells ensure that an individual remains healthy and free from infection. This study aimed to explore immune–endocrine associations involved in disease. Methods: The PsycINFO, PubMed, Web of Science, and CINAHL databases were searched for relevant articles using the following search terms and phrases: “hormones”, “hormonal responses”, “immune system”, “endocrine system”, “infection”, “immune cells”, “endocrine cells”, “infection”, “immune”, “endocrine”, and “interactions”. The search was limited to articles published between 2009 and 2023. Results: A review of ninety-three studies showed that metabolic activity levels in the body as well as energy consumption patterns are affected by feedback loops that connect the endocrine and immune systems. The associations between endocrine cells and immune cells are complex and involve a wide range of hormones, molecules, and receptors related to antipathogen responses and metabolic regulation. Conclusions: During infection, endocrine cells and immune cells interact via feedback loops to ensure optimal energy utilization and a timely response to pathogens. Therefore, the endocrine system helps to regulate systemic metabolism while controlling the outcomes of regulatory elements of the immune system.

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Articles inEndocrinology and Metabolismin 2016

Cited by 3 publications

References 61 publications

Effects of 6 Months of Dapagliflozin Treatment on Metabolic Profile and Endothelial Cell Dysfunction for Obese Type 2 Diabetes Mellitus Patients without Atherosclerotic Cardiovascular Disease

Effects of 6 Months of Dapagliflozin Treatment on Metabolic Profile and Endothelial Cell Dysfunction for Obese Type 2 Diabetes Mellitus Patients without Atherosclerotic Cardiovascular Disease

Review on Human Placental Proteomics

Insulin Resistance and Glucose Metabolism during Infection

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