Articular cartilage regeneration and tissue engineering models: a systematic review

Walter, Sebastian; Ossendorff, Robert; Schildberg, Frank A.

doi:10.1007/s00402-018-3057-z

Cited by 44 publications

(41 citation statements)

References 194 publications

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“…After acute articular surface fracture, the defect of bone and cartilage is filled with fibrin clot. The defect area of the cartilage surface is in excess of 4 to 16 mm 2 , which is usually not the result of self‐repair. For this kind of disease, the removal of free bone fragments is mainly used in.…”

Section: Discussionmentioning

confidence: 99%

Treatment of Osteochondral Fracture of the Lateral Femoral Condyle with TWINFIX Ti Suture Anchor “X”‐Shaped Internal Fixation under Arthroscopy: A Surgical Technique and Three Cases Report

Zhou

Min

Huang

2020

Orthopaedic Surgery

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Osteochondral fracture of the lateral femoral condyle is a rare intra-articular injury with or without patellar dislocation. This kind of disease is commonly seen in the knee joint sprain during strenuous activity. At present, open reduction is often used to treat osteochondral fractures. In recent years, with the development of arthroscopy, we have been able to complete the reduction and internal fixation of fractures under arthroscopy. In this paper, three cases of osteochondral fracture of lateral femoral condyle were treated with arthroscopic TWINFIX Ti suture anchor internal fixation, and good results were obtained. After operation, the fracture of femoral condyle healed well and the function of knee joint recovered gradually. Suture anchor system is mostly used to repair rotator cuff and patellar tendon. This is the first case to apply the suture anchor system to the reduction and fixation of fracture.

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Section: Discussionmentioning

confidence: 99%

Treatment of Osteochondral Fracture of the Lateral Femoral Condyle with TWINFIX Ti Suture Anchor “X”‐Shaped Internal Fixation under Arthroscopy: A Surgical Technique and Three Cases Report

Zhou

Min

Huang

2020

Orthopaedic Surgery

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“…60,70,86,161,162 As such, a systematic review by Farr et al concluded that for patients with symptomatic chondral injury, numerous techniques are available to relieve pain and improve function but until data from rigorous clinical trials are available, individual treatment decisions must still be guided by expert extrapolation of available literature using historically sound principles. 70 The authors of the present review article suggest that the peer-reviewed literature in conjunction with sound principles and basic science and preclinical data support the following guidance for clinical application to optimizing outcomes 3,18,28,61,74,117,142,[163][164][165][166][167][168][169][170][171][172] :…”

Section: Basic Science Of Outcomesmentioning

confidence: 93%

“…Tremendous effort has been focused on this critical unmet need in orthopedics and significant progress has been made in laboratory and preclinical studies using cell-based, tissue engineering, growth factordriven, gene therapy, and bioprinting strategies. 5,15,49,[142][143][144][145][146][147][148][149][150][151][152][153][154][155][156] Yet, to date, there are no successful cartilage regeneration techniques available for use in humans. 18 The scientific, regulatory, financial, and clinical requirements for use of cartilage regeneration techniques in patients are extremely challenging, such that near-term solutions cannot be expected.…”

Section: Cartilage Regenerationmentioning

confidence: 99%

Clinical Application of the Basic Science of Articular Cartilage Pathology and Treatment

et al. 2020

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The joint is an organ with each tissue playing critical roles in health and disease. Intact articular cartilage is an exquisite tissue that withstands incredible biologic and biomechanical demands in allowing movement and function, which is why hyaline cartilage must be maintained within a very narrow range of biochemical composition and morphologic architecture to meet demands while maintaining health and integrity. Unfortunately, insult, injury, and/or aging can initiate a cascade of events that result in erosion, degradation, and loss of articular cartilage such that joint pain and dysfunction ensue. Importantly, articular cartilage pathology affects the health of the entire joint and therefore should not be considered or addressed in isolation. Treating articular cartilage lesions is challenging because left alone, the tissue is incapable of regeneration or highly functional and durable repair. Nonoperative treatments can alleviate symptoms associated with cartilage pathology but are not curative or lasting. Current surgical treatments range from stimulation of intrinsic repair to whole-surface and whole-joint restoration. Unfortunately, there is a relative paucity of prospective, randomized controlled, or well-designed cohort-based clinical trials with respect to cartilage repair and restoration surgeries, such that there is a gap in knowledge that must be addressed to determine optimal treatment strategies for this ubiquitous problem in orthopedic health care. This review article discusses the basic science rationale and principles that influence pathology, symptoms, treatment algorithms, and outcomes associated with articular cartilage defects in the knee.

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“…Stem cell-based approach and chondrocyte-based approach were common choices for cartilage regenerations. The major advantage of using stem cells is that autologous transplantation can be implemented (Walter et al, 2019). Unlike chondrocytes, autologous stem cells, such as BMSCs or ADSCs, are rich in source.…”

Section: Cells For Craniofacial Cartilage Te In Am Approachesmentioning

confidence: 99%

Peer Review #4 of "Three-dimensional printing with biomaterials in craniofacial and dental tissue engineering (v0.1)"

2019

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With the development of technology, tissue engineering (TE) has been widely applied in medical field. In recent years, due to its accuracy and demands of solid freeform fabrication in TE, three-dimensional printing, also known as additive manufacturing (AM), has been applied for biological scaffolds fabrication in craniofacial and dental regeneration. In this review, we have compared several types of AM techniques and summarized their advantages and limitations. The range of printable materials used in craniofacial and dental tissue includes all the biomaterials. Thus, basic and clinical studies were discussed in this review to present the application of AM techniques in craniofacial and dental tissue and their advances during these years, which might provide information for further AM studies in craniofacial and dental TE.

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Articular cartilage regeneration and tissue engineering models: a systematic review

Cited by 44 publications

References 194 publications

Treatment of Osteochondral Fracture of the Lateral Femoral Condyle with TWINFIX Ti Suture Anchor “X”‐Shaped Internal Fixation under Arthroscopy: A Surgical Technique and Three Cases Report

Treatment of Osteochondral Fracture of the Lateral Femoral Condyle with TWINFIX Ti Suture Anchor “X”‐Shaped Internal Fixation under Arthroscopy: A Surgical Technique and Three Cases Report

Clinical Application of the Basic Science of Articular Cartilage Pathology and Treatment

Peer Review #4 of "Three-dimensional printing with biomaterials in craniofacial and dental tissue engineering (v0.1)"

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