Artifact-free robust single-shot background subtraction for optical coherence tomography

Nandakumar, Hari; Parameshwaran, Swaroop; Gamini, Rohith; Srivastava, Shailesh

doi:10.1364/osac.2.001556

Cited by 4 publications

(3 citation statements)

References 23 publications

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“…Instead, we explore a way to use the two-dimensional camera sensor in a parallel spectrometer design. The schematic of a parallel FD-OCT [14,15] setup, also known as line-field OCT [16,17] is shown in Figure 6. Such a configuration captures data for a complete B-scan in a single frame captured by the camera.…”

Section: Motivationmentioning

confidence: 99%

Low Cost Open-Source OCT Using Undergraduate Lab Components

Nandakumar¹,

Srivastava²

2020

Optical Coherence Tomography and Its Non-Medical Applications

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Instrument cost is one of the factors limiting the adoption of optical coherence tomography (OCT) from a wider range of applications. We present a couple of OCT devices using optical components which are commonly found in undergraduatelevel optics laboratories. These low-cost devices have lower signal-to-noise ratios (SNR) than top-of-the-line commercial offerings, yet can serve most of the needs of academic laboratories. A time-domain full-field (TD-FF-) OCT device has been assembled with Arduino control, which yields sub-4-μm axial and lateral resolutions. This device is useful where quick sample acquisition is not critical, but high resolution is paramount, for example with samples from material-science, or exvivo stabilized biological samples. Next, we discuss a spectral-domain (SD-) OCT device which delivers real-time video rate B-scans. This device is useful where real-time signal acquisition is desirable, for example with in-vivo biological samples. Cross-platform open-source software control for both these devices is also made available.

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Section: Motivationmentioning

confidence: 99%

Low Cost Open-Source OCT Using Undergraduate Lab Components

Nandakumar¹,

Srivastava²

2020

Optical Coherence Tomography and Its Non-Medical Applications

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“…Recently, our group demonstrated a fresh approach to background subtraction in TD-OCT, which we termed the J 0 null technique [6], briefly mentioning that the technique should also work for autocorrelation removal in FD-OCT. In this paper, we apply that technique to SD-OCT and convincingly demonstrate its utility in the removal of arbitrarily strong autocorrelation artifacts.…”

Section: Introductionmentioning

confidence: 99%

“…In conclusion, we have demonstrated a new technique for removal of autocorrelation which can work with arbitrarily strong and arbitrarily located autocorrelation artifacts. Our technique is specially suited for parallel or line-field FD-OCT devices[22,6,23,24] using spectrometers with 2-D sensors (cameras) which result in single-shot B-scans.Funding This work was not funded by any grant. Our department had infrastructure funding from the Department of Science and Technology, Government of India (DST) -DST FIST 2012-2017 SR/FST/PSI-172/2012.…”

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confidence: 99%

Complete Removal of Arbitrarily Strong and Arbitrarily Located Auto Correlation Artifacts in Spectral Domain Optical Coherence Tomography: Demonstration of an Efficient and Cost Effective Technique

Nandakumar¹,

Mallick²,

Srivastava³

2020

Preprint

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The proof-of-principle demonstration of a simple, yet effective method of autocorrelation artifact removal for optical coherence tomography (OCT) is presented using a custom-designed parallel spectral-domain OCT (SD-OCT) instrument. Our real-time method is based on time-averaged sampling of a sinusoidal phase modulation in the reference arm. Unlike other existing methods, our technique can completely eliminate arbitrarily located, arbitrarily strong autocorrelation artifacts.

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