2022
DOI: 10.1158/2159-8290.cd-22-0373
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Artificial Intelligence and Machine Learning Technologies in Cancer Care: Addressing Disparities, Bias, and Data Diversity

Abstract: Summary: Artificial intelligence (AI) and machine learning (ML) technologies have not only tremendous potential to augment clinical decision-making and enhance quality care and precision medicine efforts, but also the potential to worsen existing health disparities without a thoughtful, transparent, and inclusive approach that includes addressing bias in their design and implementation along the cancer discovery and care continuum. We discuss applications of AI/ML tools in cancer and provide … Show more

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Cited by 32 publications
(11 citation statements)
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“…AI has many advantages compared with traditional strategies for addressing health disparities, notably in its ability to uncover unexpected correlations and relationships that have remained unidentified in human-driven analyses, offering new insights. By examining variables like genetic markers, environmental exposures, social determinants, and zip codes, AI can uncover novel connections that challenge current paradigms, revealing new areas for research and interventions ( 14 ).…”
Section: Ai As a Tool To Address Health Disparitiesmentioning
confidence: 99%
See 1 more Smart Citation
“…AI has many advantages compared with traditional strategies for addressing health disparities, notably in its ability to uncover unexpected correlations and relationships that have remained unidentified in human-driven analyses, offering new insights. By examining variables like genetic markers, environmental exposures, social determinants, and zip codes, AI can uncover novel connections that challenge current paradigms, revealing new areas for research and interventions ( 14 ).…”
Section: Ai As a Tool To Address Health Disparitiesmentioning
confidence: 99%
“…Fifth and finally, there are concerns that becoming overly reliant on AI may undermine the clinician-patient relationship ( 14 ). Though algorithms cannot and should not replace human interactions in healthcare, incorporating AI as a decision support tool rather than a replacement for humans can harness and balance both the physician's expertise and machine's insights.…”
Section: Challenges To Aimentioning
confidence: 99%
“…A potentially significant, yet subtle, consequence of improper data collection might be an algorithm that performs poorly for certain subgroups or subpopulations with the targeted disease or condition as a result of under‐representation of those subgroups in the training set 30,31 . In radiology applications, it is important to be vigilant so that training/validation dataset selection incorporates safeguards to minimize underlying distortions for under‐represented and/or vulnerable populations and so that already‐existing health‐care inequities are not perpetuated or exacerbated 27,32–34 …”
Section: Datamentioning
confidence: 99%
“…For such studies, adequately sized datasets corrected for such biases are needed to analyze the effects of covariates accurately. Several recommendations for addressing biases have been presented in [ 74 ].…”
Section: Limitations Challenges and Recommendationsmentioning
confidence: 99%