Artificial Intelligence Automates Digital Image Analysis Workflow for Ki67 in Pancreatic Neuroendocrine Tumor Fine Needle Aspiration Biopsy Cell Blocks

Madrigal, Emilio; Mo, Dandan; Le, Long P.; Pitman, Martha B.

doi:10.1016/j.jasc.2019.08.153

Cited by 1 publication

(2 citation statements)

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“…Additional studies with larger comparisons of cell block and resection specimens may be needed to clarify the role of using grading in cytology and a possible incorporation of proposed guidelines in the future versions of classification systems. Novel technologies such as computer‐assisting assessment of the proliferation index using artificial intelligence may also impact this . In addition, as next‐generation sequencing (NGS) evolves, and becomes cheaper, more sensitive and readily available for cytological samples, routine incorporation in the workup of pancreaticobiliary lesions may clarify potentially “atypical” or “suspicious” cases.…”

Section: Future Perspectivesmentioning

confidence: 99%

“…Novel technologies such as computer-assisting assessment of the proliferation index using artificial intelligence may also impact this. 31 In addition, as next-generation sequencing (NGS) evolves, and becomes cheaper, more sensitive and readily available for cytological samples, routine incorporation in the workup of pancreaticobiliary lesions may clarify potentially "atypical" or "suspicious"…”

Section: Future Perspectivesmentioning

confidence: 99%

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Experience and future perspectives on the use of the Papanicolaou Society of Cytopathology Terminology System for reporting pancreaticobiliary cytology

Saieg

Pitman

2020

Diagnostic Cytopathology

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The Papanicolaou Society of Cytopathology developed a set of guidelines for reporting pancreaticobiliary cytology in 2014 (PB System), with a six‐tiered system: Nondiagnostic, Negative, Atypical, Neoplastic (Benign or Other), Suspicious, and Positive. This proposed scheme incorporates ancillary testing such as biochemical testing of cyst fluids for diagnosis and provides terminology that standardizes the category of the various diseases of the pancreas, some of which are difficult to diagnose specifically by cytology alone. Since its initial publication five and half years ago, several groups have published their experiences on the use of the PB System and have shown that most objectives proposed by the original publication have been achieved. They have shown that there is a better understanding and definition of the diagnostic categories with an associated distribution and risk of malignancy. The diagnostic categories of Neoplastic: Other, Suspicious, and Malignant show a high sensitivity and specificity for the diagnosis of malignancy. The System also provides a multi‐specialist view of pancreatic lesions, with biochemical and radiological findings being incorporated into the final pathological report. The present review summarizes these findings and discusses the future perspectives and foreseen changes that are to be incorporated to a second edition of the reporting System.

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Section: Future Perspectivesmentioning

confidence: 99%

Section: Future Perspectivesmentioning

confidence: 99%