While novel artificial intelligence and machine learning techniques are evolving and disrupting established terrestrial technologies at an unprecedented speed, their adaptation onboard satellites is seemingly lagging. A major hindrance in this regard is the need for high-quality annotated data for training such systems, which makes the development process of machine learning solutions costly, time-consuming, and inefficient. This paper presents “the OPS-SAT case”, a novel data-centric competition that seeks to address these challenges. The powerful computational capabilities of the European Space Agency’s OPS-SAT satellite are utilized to showcase the design of machine learning systems for space by using only the small amount of available labeled data, relying on the widely adopted and freely available open-source software. The generation of a suitable dataset, design and evaluation of a public data-centric competition, and results of an onboard experimental campaign by using the competition winners’ machine learning model directly on OPS-SAT are detailed. The results indicate that adoption of open standards and deployment of advanced data augmentation techniques can retrieve meaningful onboard results comparatively quickly, simplifying and expediting an otherwise prolonged development period.