2020
DOI: 10.1136/bmjdrc-2020-001596
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Artificial intelligence-enabled screening for diabetic retinopathy: a real-world, multicenter and prospective study

Abstract: IntroductionEarly screening for diabetic retinopathy (DR) with an efficient and scalable method is highly needed to reduce blindness, due to the growing epidemic of diabetes. The aim of the study was to validate an artificial intelligence-enabled DR screening and to investigate the prevalence of DR in adult patients with diabetes in China.Research design and methodsThe study was prospectively conducted at 155 diabetes centers in China. A non-mydriatic, macula-centered fundus photograph per eye was collected an… Show more

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Cited by 73 publications
(61 citation statements)
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“…[ 40 41 ] This can be an effective measure toward prevention of DR as early diagnosis and early treatment for retinopathy can reduce the incidence of severe loss of vision in a high percentage of patients with STDR. [ 6 42 ] As such, early screening for DR with an efficient and scalable method is highly needed to reduce blindness,[ 43 ] which can be achieved only by promoting awareness and knowledge regarding diabetes and its sight-threatening complications at the community level, particularly among patients with diabetes.…”
Section: Discussionmentioning
confidence: 99%
“…[ 40 41 ] This can be an effective measure toward prevention of DR as early diagnosis and early treatment for retinopathy can reduce the incidence of severe loss of vision in a high percentage of patients with STDR. [ 6 42 ] As such, early screening for DR with an efficient and scalable method is highly needed to reduce blindness,[ 43 ] which can be achieved only by promoting awareness and knowledge regarding diabetes and its sight-threatening complications at the community level, particularly among patients with diabetes.…”
Section: Discussionmentioning
confidence: 99%
“…An independent digital medical record systems described in our previous paper [ 32 34 ] was used to collect information, including age, sex; the duration of diabetes; the history of previous cardiovascular diseases; smoking and drinking status; and the use of lipid lowering, antihypertensive or hypoglycemic agents. Smoking status was defined as ‘yes’ if the participants smoked daily or almost daily.…”
Section: Methodsmentioning
confidence: 99%
“…The items “leukocyte count”, “lymphocyte count”, “lymphocytes”, and “neutrophils” (neutrophil–lymphocyte ratio) are not specific to severe disease, but clinical characteristics of severe cases present in a different manner than common cases. These severe disease-related items have also been found to be the most relevant to the studies in later stages [ 51 , 61 , 83 ]. The symptoms or indicators of common cases, such as “myalgia”, “diarrhoea”, “fatigue”, “sputum”, and “respiratory sounds”, began to decrease after the third to seventh intervals, respectively, in contrast to the heat variation of the terms relevant to severe cases.…”
Section: Resultsmentioning
confidence: 99%