In today’s world, information technology is rapidly evolving, leading to an increase in both the number and complexity of cyber threats, including phishing, malware, and social engineering attacks. The growth in the quantity and sophistication of cyber threats creates an urgent need to improve methods for protecting information systems. Artificial Intelligence (AI), particularly machine learning and deep learning technologies, shows significant potential in enhancing cybersecurity. This article is dedicated to reviewing contemporary AI-based cybersecurity methods and strategies, as well as evaluating their effectiveness in detecting and countering cyber threats. The paper analyzes recent research by both domestic and international scientists, emphasizing AI’s ability to analyze large volumes of data, uncover hidden patterns, predict potential threats, and automate incident response processes. It highlights key research directions, including anomaly detection, threat modeling, incident response automation, and ensuring the interpretability of decisions made by AI systems. Special attention is given to the integration of AI into existing cybersecurity systems and its capacity to adapt to new threats. The article also discusses the main challenges and prospects of applying AI in cybersecurity, including ethical and legal aspects such as privacy issues, decision transparency, and accountability for actions taken based on AI system decisions. Recent statistical data indicate a rapid growth in the market for AI-based cybersecurity tools, underscoring the importance and relevance of this topic in contemporary conditions. The analysis results confirm that using AI allows for automating monitoring, threat detection, and response processes, reducing incident response time and enhancing the overall protection level of information systems. At the same time, implementing AI in cybersecurity faces several challenges, such as ensuring the transparency of AI decisions and protecting against potential threats created using the same technologies. Research in this field promotes strategic development and innovation in cybersecurity, providing researchers and professionals with new tools and methods for ensuring information system security. Thus, given the rapid growth and evolution of cyber threats, studying the role of AI in cybersecurity is extremely relevant and important. It not only enhances protection efficiency but also fosters the development of new strategies and technologies to counter threats in the digital age.