“…There are several applications of machine learning and deep learning that are of clinical interest for head and neck imaging, including delineation of organs/tissues at risk or primary tumor for radiation therapy, tumor segmentation, detection, and phenotyping, and precision oncology applications, such as prediction of histopathology or molecular phenotype, response to treatment, and survival [2,[9][10][11][12]. In addition, machine learning and deep learningbased studies on specific organs of the head and neck, such as cervical lymph nodes, parotid, thyroid, and oral cavity, in which neoplasms can raise issues in the differentiation of benign vs. malignant lesions or in determining histotypes, are increasing.…”