2020
DOI: 10.1111/pan.13792
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Artificial intelligence, machine learning and the pediatric airway

Abstract: Artificial intelligence and machine learning are rapidly expanding fields with increasing relevance in anesthesia and, in particular, airway management. The ability of artificial intelligence and machine learning algorithms to recognize patterns from large volumes of complex data makes them attractive for use in pediatric anesthesia airway management. The purpose of this review is to introduce artificial intelligence, machine learning, and deep learning to the pediatric anesthesiologist. Current evidence and d… Show more

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Cited by 33 publications
(30 citation statements)
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“…Lidocaine is a membrane stabilizer that inhibits neutrophil (PMN) adhesion and aggregation, reduces oxygen radical and protein hydrolase release, stabilizes cell membranes, regulates cytokines, and suppresses excessive inflammatory responses. Inflammatory mediators LB4 and interleukin 1 α (IL-1 α ) are strong PMN chemotactic agents, inducing PMN edge, degranulation, exudation, superoxide production, and increasing vascular permeability in concert with prostaglandin E2 [ 24 , 26 ]. In vitro incubation of monocytes with different concentrations (2–20 mol/L) of lidocaine significantly inhibited the release of LB4 and IL-1 α , and micromolar concentration levels of lidocaine inhibited the release of histamine from leukocytes, mast cells, and basophils, suggesting that lidocaine can inhibit the release of some key inflammatory mediators and exert anti-inflammatory effects.…”
Section: Related Workmentioning
confidence: 99%
See 1 more Smart Citation
“…Lidocaine is a membrane stabilizer that inhibits neutrophil (PMN) adhesion and aggregation, reduces oxygen radical and protein hydrolase release, stabilizes cell membranes, regulates cytokines, and suppresses excessive inflammatory responses. Inflammatory mediators LB4 and interleukin 1 α (IL-1 α ) are strong PMN chemotactic agents, inducing PMN edge, degranulation, exudation, superoxide production, and increasing vascular permeability in concert with prostaglandin E2 [ 24 , 26 ]. In vitro incubation of monocytes with different concentrations (2–20 mol/L) of lidocaine significantly inhibited the release of LB4 and IL-1 α , and micromolar concentration levels of lidocaine inhibited the release of histamine from leukocytes, mast cells, and basophils, suggesting that lidocaine can inhibit the release of some key inflammatory mediators and exert anti-inflammatory effects.…”
Section: Related Workmentioning
confidence: 99%
“…By incorporating AI algorithms and intelligent medical assistants, the system proposes a shift from a reactive to a preventive model of care. The AI-based model proposed in [ 26 ] can help improve patient care and reduce healthcare spending. Researchers at the Massachusetts Institute of Technology have developed a system to predict the characteristics of vocal cord disease [ 31 ].…”
Section: Related Workmentioning
confidence: 99%
“…AI has also been used in pediatric anesthesia airway management, assisting pediatric patients with endotracheal intubation in the form of SmartScope. The machine-learning-based algorithm that Matava C. et al developed [ 179 ] can identify the position of the vocal cords and the airway/tracheal anatomy, helping with confirmation of intubation using bronchoscopy and video-laryngoscopy. As the study mentions, the localization of the tracheal rings is possible using segmentation module output as a tracheal GPS.…”
Section: Resultsmentioning
confidence: 99%
“…[20] Other studies have approached the role of machine learning as a complement to the physical exam, performing automatic facial analysis and detecting morphological traits related to difficult airways. [21,22] It has also been applied to monitoring pediatric airways, enhancing the detection of critical incidents and providing early warnings to the clinician. [22]…”
Section: Artificial Intelligence In Airway Managementmentioning
confidence: 99%