Purpose: The purpose of this work was to review scientific publications related to the use of visual arts in pediatric hospitals. Background: Visual arts, particularly painting, have historically played an important role in the design and atmosphere of healthcare spaces, especially hospitals. Methods: From 2000 to 2019, 79 publications located in relevant databases and manual searches were identified and analyzed. Results: Sixty of these publications include empirical studies and 19 theoretical models, comments, or reflections on the use of art in children’s hospitals. Their analysis allows us to differentiate four groups of works: (a) “environmental” includes works whose purpose is to know how visual artistic interventions in the hospital can affect the people who see them, mainly pediatric patients, families, and health workers; (b) “participatory” includes studies aimed at knowing the effect of developing visual arts activities in the hospital; (c) “exploratory” includes works whose purpose was to know more about the children’s perspective using their artistic expressions; and (d) “diagnostic” includes those that use children’s drawings as a tool to diagnose diverse processes related to the pediatric patients’ experience. Conclusions: Taken together, the works we analyzed in our study support the use of visual arts in hospitals as a resource to enhance the well-being of children and families and their experience in the hospital. We indicate two particularly relevant aspects in this sense: the importance of the visual arts in improving the symbolic quality of hospitalization settings and the communication processes that occur in these environments.