“… 1 , 2 Other risk factors include infections at a distant site (15%), diabetes (13%), trauma (12%), and infected central venous access (9%). 1 , 2 Local cellulitis progresses to an abscess and septic arthritis, leading to osteomyelitis and mediastinitis, as seen in this patient. Mediastinitis is rare in the current era of antibiotics, with complications from cardiac surgery, esophagogastroduodenoscopy, or suppurative infections of the head and neck being the most common causes.…”