2009
DOI: 10.1016/j.biopsycho.2009.05.002
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As good as it gets? A meta-analysis and systematic review of methodological quality of heart rate variability studies in functional somatic disorders

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Cited by 106 publications
(113 citation statements)
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“…In the review by Meeus et al [33], a similar result was observed but in a meta-analysis from 2009 by Tak et al [34] this difference did not reach significance for a subgroup of FM patients although the difference was significant for a compound group with functional somatic disorders. Interestingly, Tak et al [34] also reported a varying quality in the conducted studies and a large variety in the methods used to measure and analyze HRV, which makes the comparison of the results difficult.…”
Section: Hrvmentioning
confidence: 51%
See 1 more Smart Citation
“…In the review by Meeus et al [33], a similar result was observed but in a meta-analysis from 2009 by Tak et al [34] this difference did not reach significance for a subgroup of FM patients although the difference was significant for a compound group with functional somatic disorders. Interestingly, Tak et al [34] also reported a varying quality in the conducted studies and a large variety in the methods used to measure and analyze HRV, which makes the comparison of the results difficult.…”
Section: Hrvmentioning
confidence: 51%
“…Nevertheless, the SF-36 instrument, which provides a measure of physical and psychological health, showed significant differences between the two groups. The measure of HRV is affected also by methodological issues, such as temperature of the examination room and breathing frequency which were not taken under consideration when conducting the present study [34].…”
Section: Hrvmentioning
confidence: 99%
“…If relationships with physiological abnormalities are found at all, the associations are inconsistent, generally small, and the direction of causality between functional somatic syndromes and the dysfunction remains unclear, mostly leading to the conclusion that there is little convincing evidence for the causal role of a particular physiological dysfunction. This picture applies to autonomic function as indicated by heart rate variability: a metaanalysis by Tak et al (2009) found no significant difference between patients with functional somatic disorders and healthy controls after controlling for publication bias. Another review found no differences between patients with functional somatic syndromes and healthy controls in half of the studies, and some evidence of reduced cardiac vagal activity in another half, depending also on the type of functional syndrome (Tak and Rosmalen, 2010).…”
Section: Authorsmentioning
confidence: 99%
“…quality of HRV methods. 40 We additionally modified 1 item to assess whether drop-outs were accounted for in treatment studies (quality assessment tool available from authors on request). We assessed 3 general domains: appropriate selection of participants, appropriate quantification of HRV and appropriate control for confounding factors.…”
Section: Outcome Measuresmentioning
confidence: 99%