AS1411 aptamer tagged PEGylated liposomes as a smart nanocarrier for tumor-specific delivery of Withaferin A for mitigating pulmonary metastasis

Abeesh, Prathapan; Bouvet, Phillipe; Guruvayoorappan, Chandrasekaran

doi:10.1016/j.bioadv.2023.213661

Biomaterials Advances

2023

DOI: 10.1016/j.bioadv.2023.213661

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AS1411 aptamer tagged PEGylated liposomes as a smart nanocarrier for tumor-specific delivery of Withaferin A for mitigating pulmonary metastasis

Prathapan Abeesh,

Phillipe Bouvet,

Chandrasekaran Guruvayoorappan

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2024

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Cited by 4 publications

References 51 publications

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A liquid crystal-decorated aptasensing gadget for rapid monitoring of A549 cells: Future portable test kit for lung cancer diagnosis

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A liquid crystal-decorated aptasensing gadget for rapid monitoring of A549 cells: Future portable test kit for lung cancer diagnosis

Khoshbin,

Mohammadi,

Naderpour

et al. 2024

Analytica Chimica Acta

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Molecular insights into withaferin A: A holistic approach to cancer therapy

Rezaul Islam,

Rauf,

Meenakshi Rakesh

et al. 2024

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Beyond biomarkers: Exploring the diverse potential of a novel phosphoprotein in lung cancer management

Rostami,

Ranjbar,

Amiri

et al. 2024

J Cellular Molecular Medi

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In addressing the challenges of lung cancer, attention has increasingly turned to molecular diagnostics and targeted therapies, with nucleolin (NCL) assuming a pivotal role, especially in non‐small cell lung cancer. The aberrant activity and cellular distribution of NCL act as crucial biomarkers for early detection and treatment monitoring, showing a strong correlation with disease progression and patient prognosis. Elevated NCL levels signal advanced disease and poorer outcomes, underscoring its significance in evaluating disease severity and therapeutic response. Strategies targeting the molecular interactions of NCL have spurred innovative approaches to inhibit tumour growth, overcome drug resistance and improve treatment efficacy. These advancements are paving the way for personalized therapies tailored to the unique molecular profiles of patients' tumours. Consequently, NCL stands at the forefront of lung cancer management, symbolizing the move towards more precise and individualized oncology care, and marking substantial progress in therapeutic development.

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AS1411 aptamer tagged PEGylated liposomes as a smart nanocarrier for tumor-specific delivery of Withaferin A for mitigating pulmonary metastasis

Cited by 4 publications

References 51 publications

A liquid crystal-decorated aptasensing gadget for rapid monitoring of A549 cells: Future portable test kit for lung cancer diagnosis

A liquid crystal-decorated aptasensing gadget for rapid monitoring of A549 cells: Future portable test kit for lung cancer diagnosis

Molecular insights into withaferin A: A holistic approach to cancer therapy

Beyond biomarkers: Exploring the diverse potential of a novel phosphoprotein in lung cancer management

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