Ascending aortic replacement for acute type A aortic dissection in octogenarians

Suenaga, Etsuro; Sato, Manabu; Fumoto, Hideyuki

doi:10.1007/s11748-015-0613-0

Cited by 22 publications

(21 citation statements)

References 20 publications

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“…In the octogenarians though, the short-term mortality rate appeared to be better (30.9%) compared to a previous meta-analysis on the same population of study (4). Low incidences of postoperative stroke have been also reported by other authors, although in small retrospectively analyzed samples (11,14). Piccardo and colleagues (17), in their retrospective analysis of 79 octogenarians undergoing type A aortic dissection surgery, highlighted the importance of the clinical presentation as a factor affecting the surgical outcome and demonstrated that in uncomplicated AAD, early and midterm outcomes are excellent and similar to those in published series of younger patients.…”

Section: Discussionsupporting

confidence: 50%

“…For short term mortality, the analysis was conducted on four studies (6,7,9,14): results were similar to the overall analysis with a RR of 2.30 (95% CI, 1.29-4.09; P=0.0047). (95% CI, 0.30-3.56, P=0.08) for the random effect model.…”

Section: Sub-analysis In Octogenariansmentioning

confidence: 56%

“…A further screening of abstracts and full texts was conducted and a final sample of 18 studies considered relevant to our review (1,2,5,(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20). Of these, seven were excluded from the quantitative meta-analysis for different reasons.…”

Section: Prisma Preferred Reporting Items For Systematic Reviews Andmentioning

confidence: 99%

“…Only seven studies (1,6,7,(11)(12)(13)(14) reported post-operative stroke rates with an incidence in the elderly group ranging from 4.76% to 28.3 %, with a pooled rate of 19.2%. A total of 348 elderly patients over an overall population of 1,204 patients were included into this meta-analysis.…”

Section: Post-operative Strokementioning

confidence: 99%

“…Post-operative AKI was evaluated in six studies (1,6,(11)(12)(13)(14) and involved 296 elderly patients in an overall population of 997 patients (29.7%). The pooled incidence of postoperative AKI in elderly was 7.8%.…”

Section: Post-operative Acute Kidney Injurymentioning

confidence: 99%

See 4 more Smart Citations

Surgical repair of Stanford type A aortic dissection in elderly patients: a contemporary systematic review and meta-analysis

Bruno¹,

Chivasso²,

Guida³

et al. 2016

Ann. Cardiothorac. Surg.

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Background:The results of surgical treatment of type A aortic dissection (AAD) in the elderly are controversial and aggravated by a higher operative mortality rate. The studies published in this subset of patients are mainly retrospective analyses or small samples from international registries. We sought to investigate this topic by conducting a contemporary meta-analysis of the most recent observational studies.Methods: A systematic literature search was conducted for any study published in the last five years on aortic dissection treated surgically in patients 70 years and older. A pooled risk-ratio meta-analysis has been conducted three main post-operative outcomes: short-term mortality, stroke and acute kidney injury.Results: A total of 11 retrospective observational studies have been included in the quantitative metaanalysis. Pooled meta-analysis showed an increased risk of short term mortality for the elderly population 2 =14%, P=0.31) after surgery were comparable to the younger cohort of patients. Conclusions:Although affected by an increased risk of short-term mortality in the elderly, surgical repair remains the treatment of choice for AAD. The main post-operative outcomes are comparable to younger patients and the mid-term survival rates are acceptable.

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Section: Discussionsupporting

confidence: 50%