Ascite por peritonite lúpica: uma forma rara de início do lúpus eritematoso sistêmico

Júnior, Henrique Pott; Neto, André Amate; Teixeira, Maria Aparecida Barone; Provenza, José Roberto

doi:10.1590/s0482-50042012000100012

Cited by 18 publications

(7 citation statements)

References 10 publications

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“…3 Acute peritonitis secondary to SLE, as in this case study, is rare: some authors have estimated the prevalence to be less than 10% in the pediatric age group. [3][4][5] While rare, it should be considered a diagnosis of exclusion and the presentation of ascites with peritoneal signs should warrant a thorough investigation for more common causes such as spontaneous bacterial peritonitis, appendicitis, perforated viscus and malignancy.…”

Section: Discussionmentioning

confidence: 99%

The Great Imitator Strikes Again: A Case of a Lupus Flare-up Presenting Like an Acute Abdomen

Kiriakopoulos¹,

Perez²,

Hoelle³

2020

HCA Healthcare Journal of Medicine

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Description Systemic lupus erythematosus (SLE) is an autoimmune disease affecting all age groups and can manifest in various forms, often making the initial or successive presentations difficult to diagnose. Peritonitis secondary to lupus is a rare manifestation of this disease and the prevalence is said to be much lower in children. We present a case report of an adolescent male with a known history of lupus who presented to the emergency department with a clinical picture consistent with an acute surgical abdomen and underwent an appendectomy. Subsequent workup identified the culprit as a lupus-related peritonitis requiring corticosteroids for resolution.

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Section: Discussionmentioning

confidence: 99%

The Great Imitator Strikes Again: A Case of a Lupus Flare-up Presenting Like an Acute Abdomen

Kiriakopoulos¹,

Perez²,

Hoelle³

2020

HCA Healthcare Journal of Medicine

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“…Pode causar dor devido à distensão abdominal e ao efeito compressivo de vísceras. A patogênese da peritonite lúpica inclui deposição de imunocomplexos no peritônio e vasculite dos pequenos vasos do peritônio e da membrana serosa de órgãos abdominais 11 . Na peritonite lúpica crônica, anti-DNA e células LE podem ocasionalmente ser encontrados, mas não é mandatório e não excluem outras causas de ascite 12 .…”

Section: Discussionunclassified

“…O prognóstico costuma ser favorável se houver tratamento adequado, baseado na utilização de antiinflamatórios não hormonais e corticosteróides. Em casos refratários, pode ser necessário o uso de imunomoduladores ou imunossupressores 11,13 . A recorrência da ascite é frequente, mas normalmente responde bem ao aumento na dose da corticoterapia.…”

Section: Discussionunclassified

Ascite Crônica Como Manifestação Inicial Do Lúpus Eritematoso Sistêmico (Les)

2014

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“…Some patients require glucocorticoids in addition to usual medical treatment. 8,9 The potential causes of either liver enzyme abnormalities or overt liver disease include SLE itself ("lupus hepatitis"), nonsteroidal anti-inflammatory drugs (NSAIDs), and coincidental disease. Liver chemistry abnormalities may resolve with cessation of NSAID or treatment of active SLE.…”

mentioning

confidence: 99%

“…Glucocorticoids also increase the incidence of dyspepsia. 8,9 Mesenteric vasculitis is potentially life-threatening. 13 Radiographs and abdominal CT scans may show nonspecific but suggestive findings, but arteriography is usually required for diagnosis.…”

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confidence: 99%

Clinical dilemma of acute abdomen in patients with systemic lupuserythematosus: A case report

Ghavidel¹

2017

J Anal Res Clin Med

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Gastrointestinal (GI) symptoms and signs may be seen in approximately one third of patients with rheumatologic disorders as primary presentation. Some of these findings may be nondiagnostic and may be clinical diagnostic challenge. GI tract involvement by systemic lupus erythematosus (SLE) must be differentiated from adverse drug reactions of treatment agents. Abdominal pain, associated with nausea and vomiting, is seen in up to 30 percent of patients with SLE. The cause of abdominal pain does not differ significantly from that in patients without lupus. Special attention should be given to conditions that may accompany lupus such as lupus peritonitis and infection. Lupus peritonitis is very unusual clinical finding and it is worth reporting. Our patient was a young female with definite rheumatologic disorders with acute abdomen as the dominant clinical finding. Imaging findings confirmed peritoneum and small intestine involvement. Paraclinical work-up including blood analysis confirmed SLE. She was managed with prednisone and non-steroidal anti-inflammatory agents, and discharged with partial improvement. This case report shows that patients with symptoms consistent with acute abdomen in SLE remind us a clinical dilemma. There have been few reports of acute abdomen in patients with SLE in the literature. And more case reports are needed.

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Ascite por peritonite lúpica: uma forma rara de início do lúpus eritematoso sistêmico

Cited by 18 publications

References 10 publications

The Great Imitator Strikes Again: A Case of a Lupus Flare-up Presenting Like an Acute Abdomen

The Great Imitator Strikes Again: A Case of a Lupus Flare-up Presenting Like an Acute Abdomen

Ascite Crônica Como Manifestação Inicial Do Lúpus Eritematoso Sistêmico (Les)

Clinical dilemma of acute abdomen in patients with systemic lupuserythematosus: A case report

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