Ascorbic acid, Helicobacter pylori and Lewis phenotype among blacks and whites in New Orleans

Gastric Histopathology versus Vitamin C Concentrations of Whole Blood, Plasma and Gastric Juice in Young Healthy Adults

“…However, the vitamin C level of gastric juice was inversely related to the severity of chronic or active inflammation or histological H. pylori density as shown previously in other studies [6][7][8][9][10]. Our study populations were asymptomatic young, relatively healthy medical students who volunteered for endoscopy during the course of problem-based learning in chronic gastritis, one of the very common medical disorders in Chinju, Korea.…”

“…But this secretion is impaired with the onset of H. pylori-induced acute gastritis and remains impaired in H. pylori-associated chronic gastritis [4,5]. Several studies revealed that vitamin C levels of gastric juice decreased in patients with H. pylori infection [6][7][8][9][10] and returned to normal after H. pylori eradication [11][12][13]. However, most studies have been performed in a small number of volunteers or in patients with gastroduodenal disorders.…”

Nitrogenous chemicals generated from acidification of saliva influence transient lower oesophageal sphincter relaxations

“…Ascorbic acid is actively secreted in gastric juice [20]. Its median value in subjects with a healthy stomach is 250 mmol/l and is substantially lower in subjects with H. pylori infection [21], atrophic gastritis [22] and those of black ethnicity [23].…”

Gastric atrophy and atrophic gastritis — nebulous concepts in search of a definition

“…During chronic H. pylori infection all these types of repair occur, the respective proportion of each being probably modulated by environmental, genetic and bacterial factors. [32][33][34][35] Figure 4 depicts a schematic representation of two possible scenarios of damage and repair. In the first scenario the stomach responds to injury with a continuing process of restitutio ad integrum, the gastric mucosa remains hospitable for H. pylori, and chronic active gastritis persists indefinitely without developing atrophy.…”