2022
DOI: 10.1016/j.tiv.2022.105313
|View full text |Cite
|
Sign up to set email alerts
|

Ascorbic acid specifically reduces the misclassification of nonirritating reactive chemicals in the OptiSafe™ macromolecular eye irritation test

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
5

Citation Types

0
13
0

Year Published

2023
2023
2024
2024

Publication Types

Select...
3

Relationship

1
2

Authors

Journals

citations
Cited by 3 publications
(13 citation statements)
references
References 38 publications
0
13
0
Order By: Relevance
“…Opti-Safe ™ (“Optimized for Safety”) is a shelf-stable in chemico test method that consists of a proprietary macromolecular test matrix that is used to quantify the potential of an unknown test material to cause eye irritation or eye damage. Damage to macromolecules results in the loss of cell viability, and the extent of measured macromolecular damage is used to predict the toxicity of the material being tested ( Lebrun, 2018 ; 2021 ; Lebrun et al, 2021a , 2021b ; Lebrun et al, 2022 ; Choksi et al, 2020 ; Lebrun et al, 2019 , 2021a , 2021b , 2022a , 2022b ).…”
Section: Introductionmentioning
confidence: 99%
See 4 more Smart Citations
“…Opti-Safe ™ (“Optimized for Safety”) is a shelf-stable in chemico test method that consists of a proprietary macromolecular test matrix that is used to quantify the potential of an unknown test material to cause eye irritation or eye damage. Damage to macromolecules results in the loss of cell viability, and the extent of measured macromolecular damage is used to predict the toxicity of the material being tested ( Lebrun, 2018 ; 2021 ; Lebrun et al, 2021a , 2021b ; Lebrun et al, 2022 ; Choksi et al, 2020 ; Lebrun et al, 2019 , 2021a , 2021b , 2022a , 2022b ).…”
Section: Introductionmentioning
confidence: 99%
“…The score is then applied to a prediction model to classify the material tested. For a detailed description, see Lebrun et al, 2022a .…”
Section: Introductionmentioning
confidence: 99%
See 3 more Smart Citations